1X2J
Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Kelch-like ECH-associated protein 1 | polymer | 316 | 34711.9 | 1 | UniProt (Q9Z2X8) Pfam (PF01344) | Mus musculus (house mouse) | KEAP1, Cytosolic inhibitor of Nrf2 |
| 2 | B, C, D, E, F... (A) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 3 | J (A) | water | water | 18.0 | 346 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34711.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 768.5 | |
| All* | Total formula weight | 35480.4 |
