Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008134 | molecular_function | transcription factor binding |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0031463 | cellular_component | Cul3-RING ubiquitin ligase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 701 |
| Chain | Residue |
| A | HIS424 |
| A | GLU444 |
| A | PRO445 |
| A | GLU446 |
| A | ARG447 |
| A | HOH776 |
| A | HOH804 |
| A | HOH1017 |
| A | HOH1047 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 702 |
| Chain | Residue |
| A | ILE421 |
| A | ASP422 |
| A | HIS424 |
| A | TYR426 |
| A | ARG442 |
| A | PRO492 |
| A | HOH772 |
| A | HOH818 |
| A | HOH942 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 703 |
| Chain | Residue |
| A | ARG442 |
| A | ARG447 |
| A | HOH942 |
| A | HOH944 |
| A | HOH1035 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 704 |
| Chain | Residue |
| A | ILE435 |
| A | HIS437 |
| A | SER438 |
| A | SER439 |
| A | ARG494 |
| A | HOH733 |
| A | HOH744 |
| A | HOH765 |
| A | HOH778 |
| A | HOH791 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 705 |
| Chain | Residue |
| A | CYS434 |
| A | HIS436 |
| A | ARG459 |
| A | ARG494 |
| A | ARG498 |
| A | HOH785 |
| A | HOH875 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 706 |
| Chain | Residue |
| A | HIS451 |
| A | LEU452 |
| A | HOH891 |
| A | HOH897 |
| A | HOH930 |
| A | HOH1009 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 707 |
| Chain | Residue |
| A | ARG380 |
| A | ASN382 |
| A | ASN414 |
| A | HOH748 |
| A | HOH922 |
| A | HOH936 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 708 |
| Chain | Residue |
| A | ALA407 |
| A | SER408 |
| A | HOH795 |
| A | HOH820 |
| A | HOH1038 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 45 |
| Details | Repeat: {"description":"Kelch 1"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 50 |
| Details | Repeat: {"description":"Kelch 2"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"Kelch 3"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"Kelch 4"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 45 |
| Details | Repeat: {"description":"Kelch 5"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 46 |
| Details | Repeat: {"description":"Kelch 6"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Sensor for electrophilic agents","evidences":[{"source":"PubMed","id":"20498371","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"S-cGMP-cysteine","evidences":[{"source":"PubMed","id":"20498371","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"S-(2-succinyl)cysteine","evidences":[{"source":"PubMed","id":"22014577","evidenceCode":"ECO:0000269"}]} |
