1WCH
Crystal structure of PTPL1 human tyrosine phosphatase mutated in colorectal cancer - evidence for a second phosphotyrosine substrate recognition pocket
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 13 | polymer | 315 | 36087.5 | 1 | UniProt (Q12923) Pfam (PF00102) | HOMO SAPIENS (HUMAN) | PROTEIN TYROSINE PHOSPHATASE LIKE 1, PROTEIN TYROSINE PHOSPHATASE 1E, PTP-E1, HPTPE1, PTP-BAS, PROTEIN TYROSINE PHOSPHATASE PTPL1, FAS-ASSOCIATED PROTEIN TYROSINE PHOSPHATASE 1, FAP-1 |
| 2 | B, C, D (A) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 3 | E (A) | water | water | 18.0 | 280 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36087.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 284.9 | |
| All* | Total formula weight | 36372.5 |
