Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PO4 A3478 |
| Chain | Residue |
| A | ASP2378 |
| A | HOH3260 |
| A | HOH3275 |
| A | CYS2408 |
| A | SER2409 |
| A | ALA2410 |
| A | GLY2411 |
| A | ILE2412 |
| A | GLY2413 |
| A | ARG2414 |
| A | GLN2452 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 A3479 |
| Chain | Residue |
| A | SER2334 |
| A | ASN2335 |
| A | ARG2336 |
| A | HOH3277 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A3480 |
| Chain | Residue |
| A | GLN2310 |
| A | GLU2311 |
| A | ASN2372 |
| A | THR2374 |
| A | HOH3278 |
| A | HOH3279 |
| A | HOH3280 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 254 |
| Details | Domain: {"description":"Tyrosine-protein phosphatase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Region: {"description":"Substrate"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Phosphocysteine intermediate","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1bzc |
| Chain | Residue | Details |
| A | ARG2414 | |
| A | ASP2378 | |
| A | SER2415 | |
| A | CYS2408 | |
