1W82

p38 Kinase crystal structure in complex with small molecule inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	MITOGEN-ACTIVATED PROTEIN KINASE 14	polymer	360	41343.2	1	UniProt (Q16539) Pfam (PF00069)	HOMO SAPIENS (HUMAN)	P38 MAP KINASE
2	B (A)	N-[(3Z)-5-TERT-BUTYL-2-PHENYL-1,2-DIHYDRO-3H-PYRAZOL-3-YLIDENE]-N'-(4-CHLOROPHENYL)UREA	non-polymer		368.9	1	Chemie (L10)
3	C (A)	water	water		18.0	528	Chemie (HOH)

Sequence modifications

A: 1 - 1 (PDB: 1W82)
A: 2 - 360 (UniProt: Q16539)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41343.2
Non-Polymers*	Number of molecules	1
	Total formula weight	368.9
All*	Total formula weight	41712.1

*Water molecules are not included.