1W82
p38 Kinase crystal structure in complex with small molecule inhibitor
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | ESRF BEAMLINE ID14-1 |
Synchrotron site | ESRF |
Beamline | ID14-1 |
Temperature [K] | 100 |
Spacegroup name | P 21 21 21 |
Unit cell lengths | 45.684, 85.369, 126.000 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 70.710 - 2.200 |
R-factor | 0.174 |
Rwork | 0.171 |
R-free | 0.23500 |
Structure solution method | OTHER |
RMSD bond length | 0.012 |
RMSD bond angle | 1.479 |
Refinement software | REFMAC (5.2.0003A) |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 50.000 |
High resolution limit [Å] | 2.200 |
Rmerge | 0.090 |
Number of reflections | 25791 |
<I/σ(I)> | 5.6 |
Completeness [%] | 92.6 |
Redundancy | 2.2 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 |