1W63

AP1 clathrin adaptor core

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (A, C, E, G, I...)	ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT	polymer	618	69728.8	6	UniProt (P22892) Pfam (PF01602)	MUS MUSCULUS (MOUSE)	GAMMA-ADAPTIN, ADAPTOR PROTEIN COMPLEX AP-1 GAMMA-1 SUBUNIT, GOLGI ADAPTOR HA1/AP1 ADAPTIN GAMMA-1 SUBUNIT, CLATHRIN ASSEMBLY PROTEIN COMPLEX 1 GAMMA-1 LARGE CHAIN
2	B, D, F, H, J... (B, D, F, H, J...)	ADAPTER-RELATED PROTEIN COMPLEX 1 BETA 1 SUBUNIT	polymer	584	66086.4	6	UniProt (P52303) Pfam (PF01602)	RATTUS NORVEGICUS (RAT)	BETA-ADAPTIN 1, ADAPTOR PROTEIN COMPLEX AP-1 BETA-1 SUBUNIT, GOLGI ADAPTOR HA1/AP1 ADAPTIN BETA SUBUNIT, CLATHRIN ASSEMBLY PROTEIN COMPLEX 1 BETA LARGE CHAIN
3	M, N, O, P, R... (M, N, O, P, R...)	ADAPTOR-RELATED PROTEIN COMPLEX 1, MU 1 SUBUNIT	polymer	423	48590.7	6	UniProt (P35585) Pfam (PF01217) Pfam (PF00928)	MUS MUSCULUS (MOUSE)	MU-ADAPTIN 1, ADAPTOR PROTEIN COMPLEX AP-1 MU-1 SUBUNIT, GOLGI ADAPTOR HA1/AP1 ADAPTIN MU-1 SUBUNIT, CLATHRIN ASSEMBLY PROTEIN ASSEMBLY PROTEIN COMPLEX 1 MEDIUM CHAIN 1, CLATHRIN COAT ASSEMBLY PROTEIN AP47, CLATHRIN COAT ASSOCIATED PROTEIN AP47, AP-MU CHAIN FAMILY MEMBER MU1A
4	Q, S, T, U, W... (Q, S, T, U, W...)	ADAPTER-RELATED PROTEIN COMPLEX 1 SIGMA 1A SUBUNIT	polymer	158	18758.0	6	UniProt (P61967) Pfam (PF01217)	MUS MUSCULUS (MOUSE)	SIGMA-ADAPTIN 1A, ADAPTOR PROTEIN COMPLEX AP-1 SIGMA-1A SUBUNIT, GOLGI ADAPTOR HA1/AP1 ADAPTIN SIGMA-1A SUBUNIT, CLATHRIN ASSEMBLY PROTEIN COMPLEX 1 SIGMA-1A SMALL CHAIN, CLATHRIN COAT ASSEMBLY PROTEIN AP19, HA1 19 KDA SUBUNIT, SIGMA 1A SUBUNIT OF AP-1 CLATHRIN

Sequence modifications

A, C, E, G, I, K: -4 - 0 (PDB: 1W63)
A, C, E, G, I, K: 1 - 613 (UniProt: P22892)
B, D, F, H, J, L: 1 - 584 (UniProt: P52303)

PDB	External Database	Details
Met 155	Leu 155	conflict
Asp 439	Leu 439	conflict
Ser 459	Ile 459	conflict

M, N, O, P, R, V: 1 - 423 (UniProt: P35585)

PDB	External Database	Details
Phe 134	Tyr 134	conflict
Ile 406	Leu 406	conflict

Contents of the asymmetric unit

Polymers	Number of chains	24
	Total formula weight	1218983.4
All*	Total formula weight	1218983.4

*Water molecules are not included.