1VKJ

Crystal structure of heparan sulfate 3-O-sulfotransferase isoform 1 in the presence of PAP

Replaces:  1S6T

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	polymer	285	33264.0	3	UniProt (O35310) Pfam (PF00685)	Mus musculus (house mouse)
2	D, H (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	E, F, G (A)	ADENOSINE-3'-5'-DIPHOSPHATE	non-polymer		427.2	3	Chemie (A3P)
4	I, J, K (A, B, C)	water	water		18.0	178	Chemie (HOH)

Sequence modifications

A, B, C: 48 - 311 (UniProt: O35310)

PDB	External Database	Details
Met 27	-	expression tag
Gly 28	-	expression tag
Ser 29	-	expression tag
Ser 30	-	expression tag
His 31	-	expression tag
His 32	-	expression tag
His 33	-	expression tag
His 34	-	expression tag
His 35	-	expression tag
His 36	-	expression tag
Ser 37	-	expression tag
Ser 38	-	expression tag
Gly 39	-	expression tag
Leu 40	-	expression tag
Val 41	-	expression tag
Pro 42	-	expression tag
Arg 43	-	expression tag
Gly 44	-	expression tag
Ser 45	-	expression tag
His 46	-	expression tag
Met 47	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	99792.0
Non-Polymers*	Number of molecules	5
	Total formula weight	1473.7
All*	Total formula weight	101265.7

*Water molecules are not included.