1UXP
Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NADP+) | polymer | 501 | 54218.4 | 1 | UniProt (O57693) Pfam (PF00171) | THERMOPROTEUS TENAX | |
| 2 | B (A) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (AMP) | |||
| 3 | C (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 4 | D (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | E (A) | water | water | 18.0 | 331 | Chemie (HOH) |
Sequence modifications
A: 1 - 501 (UniProt: O57693)
| PDB | External Database | Details |
|---|---|---|
| Phe 378 | Leu 378 | engineered mutation |
| Leu 402 | Ser 402 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 54218.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1113.6 | |
| All* | Total formula weight | 55332.0 |
