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1UWH

The complex of wild type B-RAF and BAY439006.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
B-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASEpolymer27631422.42UniProt (P15056)
Pfam (PF07714)
HOMO SAPIENS (HUMAN)BRAF, V-RAF MURINE SARCOMA VIRAL ONCOGENE HOMOLOG B1, P94
2C, D
(A, B)
4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDEnon-polymer464.82Chemie (BAX)
3E
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
4F, G
(A, B)
waterwater18.033Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight62844.8
Non-Polymers*Number of molecules3
Total formula weight965.1
All*Total formula weight63809.9
*Water molecules are not included.

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PDB entries from 2025-12-17

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