1U8C
A novel adaptation of the integrin PSI domain revealed from its crystal structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin alpha-V | polymer | 957 | 105880.2 | 1 | UniProt (P06756) Pfam (PF01839) Pfam (PF08441) Pfam (PF20805) Pfam (PF20806) | Homo sapiens (human) | Vitronectin receptor alpha subunit, CD51 antigen |
| 2 | B (B) | Integrin beta-3 | polymer | 692 | 76650.3 | 1 | UniProt (P05106) Pfam (PF07974) Pfam (PF07965) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372) | Homo sapiens (human) | Platelet membrane glycoprotein IIIa, GPIIIa, CD61 antigen |
| 3 | C, D, E, G (C, D, E, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 4 | F, H, I (F, H, I) | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G07375KG) | |||
| 5 | J, K, L, R, S (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 6 | M, N, O, P, Q... (A, B) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) |
Sequence modifications
A: 1 - 957 (UniProt: P06756)
| PDB | External Database | Details |
|---|---|---|
| Val 753 | Ile 783 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 182530.5 | |
| Branched | Number of molecules | 7 |
| Total formula weight | 2970.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1346.5 | |
| All* | Total formula weight | 186847.8 |
