1U7F
Crystal Structure of the phosphorylated Smad3/Smad4 heterotrimeric complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Mothers against decapentaplegic homolog 3 | polymer | 198 | 22467.3 | 2 | UniProt (P84022) Pfam (PF03166) | Homo sapiens (human) | SMAD 3, Mothers against DPP homolog 3, Mad3, hMAD-3, JV15-2, hSMAD3 |
| 2 | B (B) | Mothers against decapentaplegic homolog 4 | polymer | 239 | 26060.7 | 1 | UniProt (Q13485) Pfam (PF03166) | Homo sapiens (human) | SMAD 4, Mothers against DPP homolog 4, Deletion target in pancreatic carcinoma 4, hSMAD4 |
| 3 | D, E, F (A, B, C) | water | water | 18.0 | 255 | Chemie (HOH) |
Sequence modifications
A, C: 228 - 425 (UniProt: P84022)
| PDB | External Database | Details |
|---|---|---|
| Sep 423 | Ser 423 | modified residue |
| Sep 425 | Ser 425 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 70995.2 | |
| All* | Total formula weight | 70995.2 |
