1U7F
Crystal Structure of the phosphorylated Smad3/Smad4 heterotrimeric complex
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | SITE: Necessary for heterotrimerization |
| Chain | Residue | Details |
| B | ARG515 | |
| C | LYS378 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| B | LYS428 | |
| B | LYS507 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:19135894 |
| Chain | Residue | Details |
| B | LYS519 | |
| C | SER418 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine; by TGFBR1 => ECO:0000250|UniProtKB:Q8BUN5, ECO:0000255|PROSITE-ProRule:PRU00439 |
| Chain | Residue | Details |
| A | SER422 | |
| A | SEP423 | |
| C | SER422 | |
| C | SEP423 |
