1TMM
Crystal structure of ternary complex of E.coli HPPK(W89A) with MGAMPCPP and 6-Hydroxymethylpterin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | polymer | 158 | 17851.4 | 2 | UniProt (P26281) Pfam (PF01288) | Escherichia coli | 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK, 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, PPPK |
| 2 | C, D, E, N, O (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 3 | F, J, P (A, B) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 4 | G, H, I, Q (A, B) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 5 | K, R (A, B) | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | non-polymer | 505.2 | 2 | Chemie (APC) | |||
| 6 | L, S (A, B) | 6-HYDROXYMETHYLPTERIN | non-polymer | 193.2 | 2 | Chemie (HHR) | |||
| 7 | M, T (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 8 | U, V (A, B) | water | water | 18.0 | 652 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 158 (UniProt: P26281)
| PDB | External Database | Details |
|---|---|---|
| Ala 89 | Trp 89 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35702.8 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2045.0 | |
| All* | Total formula weight | 37747.8 |
