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1TJI

Crystal Structure of the broadly neutralizing anti-HIV-1 antibody 2F5 in complex with a gp41 17mer epitope

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(L)
anti-HIV-1 antibody 2F5 Light Chainpolymer21423362.91Homo sapiens (human)
2B
(H)
anti-HIV-1 antibody 2F5 Heavy Chainpolymer23725286.81Homo sapiens (human)
3C
(P)
Envelope Glycoprotein GP41polymer182131.41UniProt (P04580)
4D, E, I
(L, H)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
5F, G, H, J, K...
(L, H)
ISOPROPYL ALCOHOLnon-polymer60.16Chemie (IPA)
6M, N, O
(L, H, P)
waterwater18.0553Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight50781.0
Non-Polymers*Number of molecules9
Total formula weight546.8
All*Total formula weight51327.8
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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