1TJI

Crystal Structure of the broadly neutralizing anti-HIV-1 antibody 2F5 in complex with a gp41 17mer epitope

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO L 771

Chain	Residue
H	ASN204
H	THR205
H	LYS206
L	ASN152

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO L 772

Chain	Residue
L	SER10
L	SER12
L	PRO141
L	GLU143
L	HOH796

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site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO H 773

Chain	Residue
H	PHE32
H	GLY33
H	SER53
H	ASP54
H	HOH1009
L	HOH775
P	LYS665

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site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE IPA H 661

Chain	Residue
H	ILE51
H	ASP55
H	LYS57
H	THR70
H	LYS71
H	THR99
H	GLY100

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IPA L 662

Chain	Residue
L	SER65
L	GLY66
L	GLU70
L	THR72

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site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA L 663

Chain	Residue
L	GLN38
L	GLY41
L	SER42

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site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IPA H 664

Chain	Residue
H	SER120
H	VAL121
H	HOH901
L	SER156

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site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IPA H 665

Chain	Residue
H	THR73
H	SER74
H	ASN76
L	SER67

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR194-HIS200
L	TYR192-HIS198

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