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1TJH

Crystal Structure of the broadly neutralizing anti-HIV-1 antibody 2F5 in complex with a gp41 11mer epitope

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(L)
anti-HIV-1 antibody 2F5 Light Chainpolymer21423362.91Homo sapiens (human)
2B
(H)
anti-HIV-1 antibody 2F5 Heavy Chainpolymer23725286.81Homo sapiens (human)
3C
(P)
Envelope glycoprotein GP41polymer131398.61UniProt (P04580)
4D, E, F, I, J...
(L, H)
ISOPROPYL ALCOHOLnon-polymer60.16Chemie (IPA)
5G, H
(H)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
6L, M, N
(L, H, P)
waterwater18.0486Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight50048.3
Non-Polymers*Number of molecules8
Total formula weight484.7
All*Total formula weight50533.0
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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