1TJH

Crystal Structure of the broadly neutralizing anti-HIV-1 antibody 2F5 in complex with a gp41 11mer epitope

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO H 771

Chain	Residue
H	ARG38
H	PRO40
H	LYS43
H	GLU46
H	HOH873
H	HOH1029

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO H 772

Chain	Residue
H	LYS71
H	GLY100
H	PRO100
L	HOH684
H	ASP55
H	LYS57
H	THR70

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE IPA H 661

Chain	Residue
H	ASN204
H	THR205
H	LYS206
L	LYS149
L	ASN152
L	LEU154

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA L 662

Chain	Residue
L	SER65
L	GLY66
L	THR72

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IPA H 663

Chain	Residue
H	LEU4
H	TRP103
H	HOH815
L	IPA666

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site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA H 664

Chain	Residue
H	THR21
H	GLN77
P	TRP670

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site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IPA L 665

Chain	Residue
H	SER28
H	THR73
H	ASN76
L	HOH839

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site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE IPA L 666

Chain	Residue
H	VAL102
H	TRP103
H	IPA663
H	HOH932
L	PRO43
L	PRO44

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR194-HIS200
L	TYR192-HIS198

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