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1TJG

Crystal Structure of the broadly neutralizing anti-HIV-1 antibody 2F5 in complex with a gp41 7mer epitope

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(L)
FAB 2F5 Light Chainpolymer21423362.91Homo sapiens (human)
2B
(H)
FAB 2F5 Heavy Chainpolymer23725286.81Homo sapiens (human)
3C
(P)
Envelope glycoprotein GP41polymer7848.91UniProt (Q75760)
4D, E, I
(L, H)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
5F, G, H, J, K...
(L, H)
ISOPROPYL ALCOHOLnon-polymer60.17Chemie (IPA)
6N, O, P
(L, H, P)
waterwater18.0391Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight49498.6
Non-Polymers*Number of molecules10
Total formula weight606.9
All*Total formula weight50105.4
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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