1TJG

Crystal Structure of the broadly neutralizing anti-HIV-1 antibody 2F5 in complex with a gp41 7mer epitope

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO H 501

Chain	Residue
H	LEU141
H	VAL169
H	SER177
H	SER179
H	HOH511
H	HOH561
L	THR178
L	HOH520

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO L 502

Chain	Residue
L	SER12
L	PRO141
L	GLU143
L	HOH506
L	SER10

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO L 503

Chain	Residue
L	GLU187
L	LYS190
L	ARG211

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IPA H 401

Chain	Residue
H	SER120
H	VAL121
H	HOH524
L	SER156

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site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IPA L 402

Chain	Residue
H	ASP54
L	LEU54

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site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IPA L 403

Chain	Residue
L	SER65
L	GLY66
L	GLU70
L	THR72

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site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE IPA L 404

Chain	Residue
H	ILE195
H	ASP208
L	GLN155
L	ASP185
L	HIS189

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site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE IPA H 405

Chain	Residue
H	GLY162
H	VAL163
H	HIS164
L	ASP167
L	LYS169

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site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IPA H 406

Chain	Residue
H	GLY100
H	HOH664
L	ARG18
L	THR72

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site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IPA H 407

Chain	Residue
H	LYS117
H	GLY118
H	SER120

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR194-HIS200
L	TYR192-HIS198

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