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1T69

Crystal Structure of human HDAC8 complexed with SAHA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Histone deacetylase 8polymer37741802.51UniProt (Q9BY41)
Pfam (PF00850)
Homo sapiens (human)HDAC8
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDEnon-polymer264.31Chemie (SHH)
Sequence modifications
A: 1 - 377 (UniProt: Q9BY41)
PDBExternal DatabaseDetails
Leu 31Pro 31conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41802.5
Non-Polymers*Number of molecules2
Total formula weight329.7
All*Total formula weight42132.2
*Water molecules are not included.

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PDB entries from 2025-07-16

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