1T69
Crystal Structure of human HDAC8 complexed with SAHA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone deacetylase 8 | polymer | 377 | 41802.5 | 1 | UniProt (Q9BY41) Pfam (PF00850) | Homo sapiens (human) | HDAC8 |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE | non-polymer | 264.3 | 1 | Chemie (SHH) |
Sequence modifications
A: 1 - 377 (UniProt: Q9BY41)
| PDB | External Database | Details |
|---|---|---|
| Leu 31 | Pro 31 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41802.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 329.7 | |
| All* | Total formula weight | 42132.2 |






