1T02
Crystal structure of a Statin bound to class II HMG-CoA reductase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | polymer | 428 | 45641.2 | 2 | UniProt (P13702) | Pseudomonas mevalonii | HMG-CoA reductase |
| 2 | C (A) | (3R,5R)-7-((1R,2R,6S,8R,8AS)-2,6-DIMETHYL-8-{[(2R)-2-METHYLBUTANOYL]OXY}-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)-3,5-DIHYDROXYHEPTANOIC ACID | non-polymer | 422.6 | 1 | Chemie (LVA) PubChem (18635107) PubChem (23624059) PubChem (25323080) PubChem (25323082) PubChem (25323084) PubChem (29982785) PubChem (44327545) PubChem (64727) PubChem (51665003) PubChem (51665005) PubChem (51665007) PubChem (51665009) PubChem (25323086) PubChem (44306552) PubChem (58879012) PubChem (58894373) PubChem (59767890) PubChem (60043959) PubChem (67234824) PubChem (3565209) PubChem (95198751) PubChem (100961143) PubChem (124824536) PubChem (92460802) PubChem (92845360) PubChem (10764718) PubChem (101610031) PubChem (9954015) PubChem (11270164) PubChem (11732591) PubChem (124824535) PubChem (124824537) PubChem (124824538) PubChem (138692981) PubChem (163902864) PubChem (171028840) PubChem (175020748) | |||
| 3 | D (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 91282.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 518.6 | |
| All* | Total formula weight | 91801.1 |
