1SPJ
STRUCTURE OF MATURE HUMAN TISSUE KALLIKREIN (HUMAN KALLIKREIN 1 OR KLK1) AT 1.70 ANGSTROM RESOLUTION WITH VACANT ACTIVE SITE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Kallikrein 1 | polymer | 238 | 26429.5 | 1 | UniProt (P06870) Pfam (PF00089) | Homo sapiens (human) | Tissue kallikrein, Kidney/pancreas/salivary gland kallikrein |
| 2 | B (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 3 | C, D (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | E (A) | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
| 5 | F (A) | water | water | 18.0 | 354 | Chemie (HOH) |
Sequence modifications
A: 16 - 246 (UniProt: P06870)
| PDB | External Database | Details |
|---|---|---|
| Glu 128 | Gln 145 | engineered mutation |
| Lys 169 | Glu 186 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26429.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 361.4 | |
| All* | Total formula weight | 26791.0 |
