1SPJ

STRUCTURE OF MATURE HUMAN TISSUE KALLIKREIN (HUMAN KALLIKREIN 1 OR KLK1) AT 1.70 ANGSTROM RESOLUTION WITH VACANT ACTIVE SITE

Summary for 1SPJ

• Entry DOI: 10.2210/pdb1spj/pdb
• Descriptor: Kallikrein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: serine protease, klk1, hk1, human kallikrein 1, human tissue kallikrein 1, tissue kallikrein, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 26790.96

Authors

Laxmikanthan, G.,Blaber, S.I.,Bernett, M.J.,Blaber, M. (deposition date: 2004-03-16, release date: 2005-01-25, Last modification date: 2021-10-27)

• Primary citation: Laxmikanthan, G.,Blaber, S.I.,Bernett, M.J.,Scarisbrick, I.A.,Juliano, M.A.,Blaber, M.; 1.70 A X-ray structure of human apo kallikrein 1: Structural changes upon peptide inhibitor/substrate binding; Proteins, 58:802-814, 2005; PubMed: 15651049; DOI: 10.1002/prot.20368

Experimental method

X-RAY DIFFRACTION (1.7 Å)