1SMY
Structural basis for transcription regulation by alarmone ppGpp
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, K, L | DNA-directed RNA polymerase alpha chain | polymer | 315 | 35056.2 | 4 | UniProt (Q9Z9H6) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118) In PDB | Thermus thermophilus | RNAP alpha subunit, Transcriptase alpha chain, RNA polymerase alpha subunit |
| 2 | C, M | DNA-directed RNA polymerase beta chain | polymer | 1119 | 125436.5 | 2 | UniProt (Q8RQE9) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560) In PDB | Thermus thermophilus | RNAP beta subunit, Transcriptase beta chain, RNA polymerase beta subunit |
| 3 | D, N | DNA-directed RNA polymerase beta' chain | polymer | 1524 | 170997.4 | 2 | UniProt (Q8RQE8) Pfam (PF04997) Pfam (PF21668) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB | Thermus thermophilus | RNAP beta' subunit, Transcriptase beta' chain, RNA polymerase beta' subunit |
| 4 | E, O | RNA POLYMERASE OMEGA SUBUNIT | polymer | 99 | 11521.2 | 2 | Pfam (PF01192) UniProt (by SIFTS) (Q8RQE7) In PDB | Thermus thermophilus | |
| 5 | F, P | principal sigma factor | polymer | 423 | 48568.0 | 2 | GenBank (4239959) Pfam (PF00140) Pfam (PF04542) Pfam (PF04539) Pfam (PF04545) UniProt (by SIFTS) (Q72L95) In PDB | Thermus thermophilus | |
| 6 | A, B, C, D, E... | MAGNESIUM ION | non-polymer | 24.3 | 362 | Chemie (MG) | |||
| 7 | D, N | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 8 | N | GUANOSINE-5',3'-TETRAPHOSPHATE | non-polymer | 603.2 | 2 | Chemie (G4P) | |||
| 9 | water | water | 18.0 | 9031 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 853271.0 | |
| Non-Polymers* | Number of molecules | 368 |
| Total formula weight | 10266.4 | |
| All* | Total formula weight | 863537.3 |
