1SMY

Structural basis for transcription regulation by alarmone ppGpp

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, G, H (A, B, K, L)	DNA-directed RNA polymerase alpha chain	polymer	315	35056.2	4	UniProt (Q9Z9H6) Pfam (PF01193) Pfam (PF01000) Pfam (PF03118)	Thermus thermophilus	RNAP alpha subunit, Transcriptase alpha chain, RNA polymerase alpha subunit
2	C, I (C, M)	DNA-directed RNA polymerase beta chain	polymer	1119	125436.5	2	UniProt (Q8RQE9) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF10385) Pfam (PF00562) Pfam (PF04560)	Thermus thermophilus	RNAP beta subunit, Transcriptase beta chain, RNA polymerase beta subunit
3	D, J (D, N)	DNA-directed RNA polymerase beta' chain	polymer	1524	170997.4	2	UniProt (Q8RQE8) Pfam (PF04997) Pfam (PF21668) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998)	Thermus thermophilus	RNAP beta' subunit, Transcriptase beta' chain, RNA polymerase beta' subunit
4	E, K (E, O)	RNA POLYMERASE OMEGA SUBUNIT	polymer	99	11521.2	2	Pfam (PF01192) UniProt (by SIFTS) (Q8RQE7)	Thermus thermophilus
5	F, L (F, P)	principal sigma factor	polymer	423	48568.0	2	GenBank (4239959) Pfam (PF00140) Pfam (PF04542) Pfam (PF04539) Pfam (PF04545) UniProt (by SIFTS) (Q72L95)	Thermus thermophilus
6	AA, AB, AC, AD, AE... (A, B, C, D, E...)	MAGNESIUM ION	non-polymer		24.3	362	Chemie (MG)
7	AF, KN, LN, ZE (D, N)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
8	ON, PN (N)	GUANOSINE-5',3'-TETRAPHOSPHATE	non-polymer		603.2	2	Chemie (G4P)
9	AO, BO, QN, RN, SN... (O, P, A, B, C...)	water	water		18.0	9031	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	853271.0
Non-Polymers*	Number of molecules	368
	Total formula weight	10266.4
All*	Total formula weight	863537.3

*Water molecules are not included.