Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1SMY

Structural basis for transcription regulation by alarmone ppGpp

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000428	cellular_component	DNA-directed RNA polymerase complex
A	0003677	molecular_function	DNA binding
A	0003899	molecular_function	DNA-directed RNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0006351	biological_process	DNA-templated transcription
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0046983	molecular_function	protein dimerization activity
B	0000428	cellular_component	DNA-directed RNA polymerase complex
B	0003677	molecular_function	DNA binding
B	0003899	molecular_function	DNA-directed RNA polymerase activity
B	0005737	cellular_component	cytoplasm
B	0006351	biological_process	DNA-templated transcription
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0046983	molecular_function	protein dimerization activity
C	0000428	cellular_component	DNA-directed RNA polymerase complex
C	0003677	molecular_function	DNA binding
C	0003899	molecular_function	DNA-directed RNA polymerase activity
C	0006351	biological_process	DNA-templated transcription
C	0016740	molecular_function	transferase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0032549	molecular_function	ribonucleoside binding
C	0034062	molecular_function	5'-3' RNA polymerase activity
D	0000287	molecular_function	magnesium ion binding
D	0000428	cellular_component	DNA-directed RNA polymerase complex
D	0003677	molecular_function	DNA binding
D	0003899	molecular_function	DNA-directed RNA polymerase activity
D	0005515	molecular_function	protein binding
D	0006351	biological_process	DNA-templated transcription
D	0008270	molecular_function	zinc ion binding
D	0016740	molecular_function	transferase activity
D	0016779	molecular_function	nucleotidyltransferase activity
D	0034062	molecular_function	5'-3' RNA polymerase activity
D	0046872	molecular_function	metal ion binding
E	0000428	cellular_component	DNA-directed RNA polymerase complex
E	0003677	molecular_function	DNA binding
E	0003899	molecular_function	DNA-directed RNA polymerase activity
E	0006351	biological_process	DNA-templated transcription
E	0016740	molecular_function	transferase activity
E	0016779	molecular_function	nucleotidyltransferase activity
E	0034062	molecular_function	5'-3' RNA polymerase activity
F	0003677	molecular_function	DNA binding
F	0003700	molecular_function	DNA-binding transcription factor activity
F	0005737	cellular_component	cytoplasm
F	0006351	biological_process	DNA-templated transcription
F	0006352	biological_process	DNA-templated transcription initiation
F	0006355	biological_process	regulation of DNA-templated transcription
F	0010468	biological_process	regulation of gene expression
F	0016987	molecular_function	sigma factor activity
F	2000142	biological_process	regulation of DNA-templated transcription initiation
K	0000428	cellular_component	DNA-directed RNA polymerase complex
K	0003677	molecular_function	DNA binding
K	0003899	molecular_function	DNA-directed RNA polymerase activity
K	0005737	cellular_component	cytoplasm
K	0006351	biological_process	DNA-templated transcription
K	0016740	molecular_function	transferase activity
K	0016779	molecular_function	nucleotidyltransferase activity
K	0034062	molecular_function	5'-3' RNA polymerase activity
K	0046983	molecular_function	protein dimerization activity
L	0000428	cellular_component	DNA-directed RNA polymerase complex
L	0003677	molecular_function	DNA binding
L	0003899	molecular_function	DNA-directed RNA polymerase activity
L	0005737	cellular_component	cytoplasm
L	0006351	biological_process	DNA-templated transcription
L	0016740	molecular_function	transferase activity
L	0016779	molecular_function	nucleotidyltransferase activity
L	0034062	molecular_function	5'-3' RNA polymerase activity
L	0046983	molecular_function	protein dimerization activity
M	0000428	cellular_component	DNA-directed RNA polymerase complex
M	0003677	molecular_function	DNA binding
M	0003899	molecular_function	DNA-directed RNA polymerase activity
M	0006351	biological_process	DNA-templated transcription
M	0016740	molecular_function	transferase activity
M	0016779	molecular_function	nucleotidyltransferase activity
M	0032549	molecular_function	ribonucleoside binding
M	0034062	molecular_function	5'-3' RNA polymerase activity
N	0000287	molecular_function	magnesium ion binding
N	0000428	cellular_component	DNA-directed RNA polymerase complex
N	0003677	molecular_function	DNA binding
N	0003899	molecular_function	DNA-directed RNA polymerase activity
N	0005515	molecular_function	protein binding
N	0006351	biological_process	DNA-templated transcription
N	0008270	molecular_function	zinc ion binding
N	0016740	molecular_function	transferase activity
N	0016779	molecular_function	nucleotidyltransferase activity
N	0034062	molecular_function	5'-3' RNA polymerase activity
N	0046872	molecular_function	metal ion binding
O	0000428	cellular_component	DNA-directed RNA polymerase complex
O	0003677	molecular_function	DNA binding
O	0003899	molecular_function	DNA-directed RNA polymerase activity
O	0006351	biological_process	DNA-templated transcription
O	0016740	molecular_function	transferase activity
O	0016779	molecular_function	nucleotidyltransferase activity
O	0034062	molecular_function	5'-3' RNA polymerase activity
P	0003677	molecular_function	DNA binding
P	0003700	molecular_function	DNA-binding transcription factor activity
P	0005737	cellular_component	cytoplasm
P	0006351	biological_process	DNA-templated transcription
P	0006352	biological_process	DNA-templated transcription initiation
P	0006355	biological_process	regulation of DNA-templated transcription
P	0010468	biological_process	regulation of gene expression
P	0016987	molecular_function	sigma factor activity
P	2000142	biological_process	regulation of DNA-templated transcription initiation

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 9209

Chain	Residue
A	ALA52
A	LYS83
A	LEU85
A	VAL170
A	HOH9623

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 9212

Chain	Residue
A	HOH9777
A	LYS159
A	ASP160
A	ARG161
A	ILE162

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 9224

Chain	Residue
A	ASP74
C	PHE628
C	HOH2048
C	HOH9863

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 9227

Chain	Residue
A	ARG88
A	GLU121
A	ILE122
A	MET123

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG A 9254

Chain	Residue
A	ASN212

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 9268

Chain	Residue
A	MG9437
A	HOH9637
A	HOH9749

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 9273

Chain	Residue
A	GLU59
A	ASN139
A	HOH9627
A	HOH9651
A	HOH9801

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG A 9295

Chain	Residue
A	LYS107
A	ASP113

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG A 9327

Chain	Residue
A	TRP200
A	MG9464

site_id	AD1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9417

Chain	Residue
D	GLU1152
D	ARG1159
D	HOH9677

site_id	AD2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9419

Chain	Residue
D	ASP107
D	ARG586
D	THR1444

site_id	AD3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9421

Chain	Residue
D	HOH2941
D	HOH3121

site_id	AD4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9428

Chain	Residue
D	LYS165
D	HOH2251
D	HOH9939

site_id	AD5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9434

Chain	Residue
D	THR808
D	HOH3016

site_id	AD6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9435

Chain	Residue
D	LYS7

site_id	AD7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9439

Chain	Residue
D	HOH2207
D	HOH2209
D	MG9390

site_id	AD8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9440

Chain	Residue
D	HOH2305
D	HOH2368
D	HOH9578

site_id	AD9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9443

Chain	Residue
D	ASP1090
D	TYR1093
D	HOH2364
D	HOH2905

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 9329

Chain	Residue
A	HOH9688
P	LYS154
P	GLU158
P	GLN161

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG A 9334

Chain	Residue
A	SER93
A	HOH9725

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 9365

Chain	Residue
A	ARG175
A	ASP202
A	HOH9659

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 9368

Chain	Residue
A	GLN188
A	ARG189
A	LEU192

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG A 9394

Chain	Residue
A	MG9486
A	HOH9729

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 9423

Chain	Residue
A	ASN91
A	SER93
A	HOH9636
A	HOH9833

site_id	BC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG A 9437

Chain	Residue
A	MG9268

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 9442

Chain	Residue
A	ARG18
A	ARG88
A	LEU90
A	GLU121
A	HOH9556

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG A 9462

Chain	Residue
A	ASP191
C	LYS938

site_id	BD1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9447

Chain	Residue
D	HOH2238
D	HOH2836
D	HOH9798

site_id	BD2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9448

Chain	Residue
D	GLN636
D	LYS638

site_id	BD3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9452

Chain	Residue
D	HOH2295

site_id	BD4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG D 9455

Chain	Residue
D	LYS960
D	ARG1058
D	SER1059
D	SER1060
D	HOH2237
D	MG9233
D	MG9380
D	HOH9638

site_id	BD5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 9456

Chain	Residue
C	PHE425
C	ARG428
C	HOH2470
D	ALA1082
D	LEU1086

site_id	BD6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9460

Chain	Residue
D	TYR868
D	MET869

site_id	BD7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9461

Chain	Residue
D	VAL1503

site_id	BD8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 9467

Chain	Residue
D	LYS62
D	TYR63
D	GLU74
D	HOH2359
D	HOH2689

site_id	BD9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9469

Chain	Residue
D	HOH2109

site_id	CC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG A 9464

Chain	Residue
A	ARG176
A	MG9327

site_id	CC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 9473

Chain	Residue
A	GLU133
A	HOH9571
C	VAL645

site_id	CC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 9486

Chain	Residue
A	GLU134
A	MG9394
C	LYS605

site_id	CC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG A 9517

Chain	Residue
A	HOH9695
A	HOH9808

site_id	CC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG A 9520

Chain	Residue
A	LYS159

site_id	CC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG A 9521

Chain	Residue
A	PRO106

site_id	CC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 9543

Chain	Residue
A	ASN91
A	HOH9734
A	HOH9791

site_id	CC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG A 9544

Chain	Residue
B	HOH9722

site_id	CC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 9555

Chain	Residue
A	TYR224
A	HOH9644
A	HOH9771

site_id	CD1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9470

Chain	Residue
D	HOH2634
D	HOH2978
D	MG9379

site_id	CD2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9472

Chain	Residue
D	GLU998
D	HOH2957
D	HOH9679
P	HOH8016

site_id	CD3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9475

Chain	Residue
D	HOH2776
D	HOH2905

site_id	CD4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9477

Chain	Residue
D	HOH3092
D	HOH9976
E	HOH9676

site_id	CD5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9478

Chain	Residue
D	HOH2292
D	HOH2492
D	MG9342

site_id	CD6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9479

Chain	Residue
F	HOH2081

site_id	CD7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9480

Chain	Residue
D	ARG1087
D	HOH9624

site_id	CD8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9481

Chain	Residue
D	ASP55
D	TYR56
D	LYS82

site_id	CD9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9482

Chain	Residue
D	GLU1161
D	HOH9751

site_id	DC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 9228

Chain	Residue
B	PHE65
B	SER66
B	THR67
B	ASP74

site_id	DC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 9230

Chain	Residue
A	VAL13
A	HOH9718
B	GLN229
D	HOH2139

site_id	DC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 9235

Chain	Residue
B	GLU73
B	GLU77
B	ILE78
B	HOH9632
B	HOH9639

site_id	DC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG B 9256

Chain	Residue
B	ARG146
B	HOH9605

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 9260

Chain	Residue
B	PHE23
B	THR196
B	LEU197
B	ARG198

site_id	DC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG B 9280

Chain	Residue
B	HIS63
B	PHE65
B	SER66

site_id	DC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 9281

Chain	Residue
D	ASP685
D	HOH2171
D	HOH2358
B	GLN188

site_id	DC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG B 9306

Chain	Residue
B	PRO152
D	ILE857
D	HOH2279

site_id	DC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 9311

Chain	Residue
B	SER93
B	LEU94
B	ASP119
B	HOH9651

site_id	DD1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9490

Chain	Residue
D	GLU69
D	GLY70
D	LYS71
D	HOH2832

site_id	DD2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9492

Chain	Residue
D	HOH3228

site_id	DD3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9498

Chain	Residue
D	ARG1213
D	MG9258

site_id	DD4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9499

Chain	Residue
D	GLU891
D	MG9384

site_id	DD5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9502

Chain	Residue
D	ARG921

site_id	DD6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9503

Chain	Residue
D	HOH2122
D	HOH2897

site_id	DD7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9505

Chain	Residue
D	HOH2275
D	MG9533

site_id	DD8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9506

Chain	Residue
D	HOH2890

site_id	DD9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9510

Chain	Residue
N	LEU227
N	HOH2644
P	HOH1787

site_id	EC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 9412

Chain	Residue
B	GLN180
B	GLU182
B	MG9491
B	HOH9576

site_id	EC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 9413

Chain	Residue
B	GLN95
B	ASP145
B	ARG146
B	HOH9657

site_id	EC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG B 9420

Chain	Residue
A	HOH9588
B	ARG189

site_id	EC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG B 9426

Chain	Residue
B	ARG219

site_id	EC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 9427

Chain	Residue
B	GLU29
B	ARG30
B	ASP191
B	LEU192
B	ASP193
B	HOH9697

site_id	EC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG B 9446

Chain	Residue
B	HOH9644
B	HOH9704
B	HOH9723

site_id	EC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG B 9458

Chain	Residue
B	VAL71
B	LYS72

site_id	EC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 9485

Chain	Residue
B	THR206
B	LEU208
B	MG9552
B	HOH9561
B	HOH9668
B	HOH9691

site_id	EC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG B 9488

Chain	Residue
B	MG9560

site_id	ED1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9512

Chain	Residue
D	ALA1502
D	MG9529
E	HOH9640

site_id	ED2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9515

Chain	Residue
D	MG9392

site_id	ED3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9523

Chain	Residue
D	ALA100
D	MET512
D	ILE513
D	HOH9584

site_id	ED4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 9527

Chain	Residue
B	ARG185
B	HOH9611
B	HOH9613
D	LYS646
D	TRP688
D	HOH2534

site_id	ED5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9528

Chain	Residue
B	HOH9604
D	GLU888

site_id	ED6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9529

Chain	Residue
D	MG9512
E	HOH9640

site_id	ED7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9532

Chain	Residue
D	LEU823
D	HOH2121
D	HOH2487

site_id	ED8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9533

Chain	Residue
C	HOH9892
D	ASP682
D	MG9505

site_id	ED9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 9535

Chain	Residue
D	ASN143
D	HOH2681
D	HOH3065
D	HOH3179
D	MG9325

site_id	FC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG B 9491

Chain	Residue
B	GLU182
B	MG9412

site_id	FC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG B 9541

Chain	Residue
B	HOH9635
B	HOH9758

site_id	FC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG B 9552

Chain	Residue
B	THR15
B	LEU208
B	MG9485

site_id	FC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG B 9560

Chain	Residue
B	MG9488

site_id	FC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9202

Chain	Residue
C	GLU685
D	HOH9563
N	G4P9100
N	HOH9208
N	HOH9209

site_id	FC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9210

Chain	Residue
C	ASP686
C	ALA687
C	ILE688
C	ASN845
C	GLY847

site_id	FC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 9213

Chain	Residue
C	VAL461
C	ASP462
C	GLU463
C	LEU464
C	GLY465
C	PHE466

site_id	FC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9217

Chain	Residue
N	G4P9100
N	HOH9210

site_id	FC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9219

Chain	Residue
C	ARG292
C	LYS299

site_id	FD1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9536

Chain	Residue
L	HOH1491

site_id	FD2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9539

Chain	Residue
D	TYR63
D	VAL72
D	HOH3032

site_id	FD3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9546

Chain	Residue
D	ILE32
D	MET527
D	MG9261

site_id	FD4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9547

Chain	Residue
D	HOH3247

site_id	FD5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9548

Chain	Residue
N	HOH9528

site_id	FD6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 9557

Chain	Residue
D	GLU219
D	ARG220
D	ALA221
D	HOH2084
D	HOH9564

site_id	FD7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9559

Chain	Residue
D	TRP897
D	LEU902

site_id	FD8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG E 9249

Chain	Residue
E	THR50
E	MG9484

site_id	FD9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG E 9275

Chain	Residue
E	LYS87

site_id	GC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9221

Chain	Residue
C	PHE679
C	ASP680
C	GLY681
C	TYR682
C	ASN683

site_id	GC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 9222

Chain	Residue
C	LYS518
C	GLY519
C	HOH9564
C	HOH9953

site_id	GC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9223

Chain	Residue
C	ARG353
C	GLY354
C	GLU357

site_id	GC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 9231

Chain	Residue
C	ARG586
C	ASP590
C	MG9255
C	HOH9871

site_id	GC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 9238

Chain	Residue
C	PRO1012
C	LEU1021
C	GLY1022
C	GLY1023
C	GLN1026
C	HOH9843

site_id	GC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9239

Chain	Residue
C	VAL943
C	VAL973
C	LEU974
C	PRO982
C	ILE983

site_id	GC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9243

Chain	Residue
C	HIS434
C	TYR435
C	GLY436
C	ARG437
C	ILE438

site_id	GC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9255

Chain	Residue
C	ARG586
C	HOH2096
C	MG9231

site_id	GC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9257

Chain	Residue
C	GLN1019
C	ARG1031
C	HOH2055
D	GLN616
F	MG9244

site_id	GD1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG E 9288

Chain	Residue
E	PRO81
E	HOH9619

site_id	GD2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG E 9341

Chain	Residue
E	THR70
E	GLY71
E	ARG72
E	LEU73

site_id	GD3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG E 9352

Chain	Residue
D	ARG760
E	GLU3
E	PRO4
E	MET65

site_id	GD4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG E 9366

Chain	Residue
D	HOH9644
E	ARG84
E	GLU88
E	ARG91
E	HOH9574

site_id	GD5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG E 9373

Chain	Residue
E	GLU90
E	GLU96

site_id	GD6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG E 9389

Chain	Residue
D	HOH2117
E	LYS25
E	HOH9692

site_id	GD7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG E 9431

Chain	Residue
E	MET12
E	HOH9661
E	HOH9710

site_id	GD8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG E 9432

Chain	Residue
D	LYS1490
E	ASN37
E	THR38
E	TYR93
E	HOH9650

site_id	GD9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG E 9449

Chain	Residue
D	HOH3137
E	MG9484

site_id	HC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9259

Chain	Residue
C	MG9519
P	HIS263
P	GLU266

site_id	HC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 9263

Chain	Residue
C	ALA574
C	GLN575
C	GLU662
C	MG9316

site_id	HC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9264

Chain	Residue
C	THR888
C	HIS889
C	GLY970
C	VAL988
C	VAL989

site_id	HC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9266

Chain	Residue
C	PHE684
C	ASN872
C	LEU874
C	HOH2136
D	ASP784

site_id	HC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9267

Chain	Residue
C	GLY416
C	ARG420
C	HOH9952

site_id	HC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9272

Chain	Residue
C	PHE1032
C	MET1052
D	HIS748

site_id	HC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9282

Chain	Residue
C	PRO144
C	LEU165
C	ARG265
C	ARG266
C	HOH9649

site_id	HC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9284

Chain	Residue
C	PRO150
C	ASP151
C	PRO152

site_id	HC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9287

Chain	Residue
C	ALA1065
C	GLU1068
C	ALA1069
C	GLU1074
C	PRO1077

site_id	HD1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG E 9457

Chain	Residue
E	HOH9557

site_id	HD2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG E 9484

Chain	Residue
D	HOH3137
E	MG9249
E	MG9449

site_id	HD3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG E 9494

Chain	Residue
E	GLU52
E	HOH9667

site_id	HD4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG E 9551

Chain	Residue
E	HOH9631

site_id	HD5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG F 9229

Chain	Residue
F	ARG184
F	ILE188

site_id	HD6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG F 9244

Chain	Residue
C	MG9257
D	GLN616
D	HOH2635
F	PHE328
F	HOH9925

site_id	HD7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 9245

Chain	Residue
F	PRO334
F	GLU336
F	HOH9836

site_id	HD8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG F 9250

Chain	Residue
F	PHE389
F	PHE390
F	MG9407
F	HOH9599

site_id	HD9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG F 9251

Chain	Residue
C	PHE778
F	LYS409
F	GLU412
F	SER413
F	ARG416
F	HOH9600
F	HOH9720

site_id	IC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 9289

Chain	Residue
C	HOH2083

site_id	IC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9292

Chain	Residue
C	GLN1050
D	HOH2380

site_id	IC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 9293

Chain	Residue
C	TYR494

site_id	IC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9299

Chain	Residue
C	ARG353
C	MG9397

site_id	IC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 9300

Chain	Residue
C	GLY7
C	ASP907
C	GLY908
C	LYS910

site_id	IC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9313

Chain	Residue
C	GLU232
C	HOH2727

site_id	IC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 9316

Chain	Residue
C	ALA574
C	ARG642
C	SER661
C	GLU662
C	HOH2028
C	MG9263

site_id	IC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9320

Chain	Residue
C	GLN834
C	HOH2073

site_id	IC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9321

Chain	Residue
C	SER366
C	LYS371

site_id	ID1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG F 9270

Chain	Residue
F	ARG372
F	LYS373
F	GLY378
F	HOH2056
F	HOH9666

site_id	ID2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 9278

Chain	Residue
F	ARG142
F	GLY146
F	HOH9740

site_id	ID3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 9290

Chain	Residue
F	HOH2171
K	ARG185
K	HOH2002

site_id	ID4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG F 9297

Chain	Residue
D	ASN569
D	HOH2196
F	PRO80
F	VAL81
F	TYR84

site_id	ID5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 9298

Chain	Residue
F	ARG132
F	GLU181
F	ARG184

site_id	ID6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG F 9302

Chain	Residue
D	LYS131
D	ARG572
D	HOH9825
F	ASP79
F	GLN83

site_id	ID7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG F 9303

Chain	Residue
F	PRO286
F	THR287
F	GLU290
F	ILE291

site_id	ID8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG F 9305

Chain	Residue
F	GLY322
F	ASP323
F	HOH9633
F	HOH9696

site_id	ID9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG F 9309

Chain	Residue
F	HOH9884

site_id	JC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9328

Chain	Residue
C	LYS1105
C	HOH2201

site_id	JC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 9330

Chain	Residue
C	HOH2751

site_id	JC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9335

Chain	Residue
C	ASP81
C	TYR629

site_id	JC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 9338

Chain	Residue
C	LYS61
C	MET359
C	HOH2063
C	HOH9985

site_id	JC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9339

Chain	Residue
C	PRO1012
F	PRO334

site_id	JC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9345

Chain	Residue
C	ARG8
C	ARG10
C	HOH2553
C	MG9534
C	HOH9878

site_id	JC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 9346

Chain	Residue
C	GLY477
C	ILE508
C	PRO526
C	HOH2832
C	MG9378
N	ARG35

site_id	JC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9347

Chain	Residue
C	ARG292
C	ASP295
C	GLU297

site_id	JC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9348

Chain	Residue
C	GLU709
C	VAL822
C	ARG824

site_id	JD1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG F 9310

Chain	Residue
D	HOH2183
F	LEU349
F	LEU350
F	LEU422

site_id	JD2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG F 9323

Chain	Residue
F	GLU158
F	LYS162
F	HOH9697
K	HOH4193

site_id	JD3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 9324

Chain	Residue
M	GLY316
M	VAL317
M	HOH2371

site_id	JD4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG F 9326

Chain	Residue
F	THR203
F	GLY204

site_id	JD5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG F 9340

Chain	Residue
F	HOH9839
K	HOH6577

site_id	JD6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 9374

Chain	Residue
F	LEU271
F	THR307
F	LEU308

site_id	JD7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG F 9375

Chain	Residue
F	GLU189

site_id	JD8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG F 9382

Chain	Residue
F	GLU384
F	GLY387
F	HOH2142
F	HOH9764
F	HOH9813

site_id	JD9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG F 9388

Chain	Residue
F	HOH9779

site_id	KC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 9354

Chain	Residue
C	GLU301

site_id	KC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9356

Chain	Residue
C	ASP396
C	HOH9619

site_id	KC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9358

Chain	Residue
C	HOH2445
C	HOH9764

site_id	KC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9359

Chain	Residue
C	ARG168
C	HOH2130
C	HOH2484

site_id	KC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9364

Chain	Residue
C	GLU913
C	HOH2044
C	HOH2278
C	MG9454
C	HOH9962

site_id	KC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 9367

Chain	Residue
C	ASN330
C	HOH2160
C	MG9509
C	HOH9923

site_id	KC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9371

Chain	Residue
C	HIS1006
D	ARG628

site_id	KC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9378

Chain	Residue
C	GLY477
C	HOH2832
C	MG9346
C	HOH9591
N	ARG35

site_id	KC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9381

Chain	Residue
C	GLU527
C	HOH2619
P	HOH4201

site_id	KD1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG F 9398

Chain	Residue
F	ARG249

site_id	KD2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG F 9407

Chain	Residue
F	VAL386
F	GLY387
F	PHE389
F	PHE390
F	MG9250
F	HOH9617

site_id	KD3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG F 9414

Chain	Residue
F	SER362
F	ILE400
F	MG9463
F	HOH9901

site_id	KD4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 9424

Chain	Residue
F	HOH9733
F	HOH9804
F	HOH9843

site_id	KD5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG F 9425

Chain	Residue
F	TYR329

site_id	KD6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG F 9436

Chain	Residue
F	HOH9877
F	HOH9755
F	HOH9762
F	HOH9781

site_id	KD7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG F 9445

Chain	Residue
F	GLU324
F	LYS325

site_id	KD8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG F 9450

Chain	Residue
F	HOH9820
N	HOH9254
N	HOH9731
N	HOH9882

site_id	KD9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 9453

Chain	Residue
C	HOH2517
F	HOH9729
F	HOH9930

site_id	LC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 9383

Chain	Residue
C	LEU200
C	PHE298
C	LYS299
C	ASP300

site_id	LC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9385

Chain	Residue
C	LEU66
C	VAL355
C	LEU372
C	HOH2671
C	HOH2843

site_id	LC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9387

Chain	Residue
C	LYS167
C	ARG168

site_id	LC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9395

Chain	Residue
C	GLU20
C	ARG28

site_id	LC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 9396

Chain	Residue
C	ASN374
C	SER375
C	PRO377
C	LEU378

site_id	LC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9397

Chain	Residue
C	VAL346
C	ARG353
C	MG9299

site_id	LC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9405

Chain	Residue
C	HOH2204
C	HOH2632

site_id	LC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 9408

Chain	Residue
C	GLU551
C	PHE906
C	ASP907
C	GLY908

site_id	LC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9411

Chain	Residue
C	HOH2775
C	MG9519
P	HIS263

site_id	LD1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG F 9463

Chain	Residue
F	SER362
F	MG9414

site_id	LD2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG F 9468

Chain	Residue
F	HOH9683

site_id	LD3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG F 9471

Chain	Residue
F	HOH9754
F	HOH9870

site_id	LD4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 9483

Chain	Residue
F	GLY391
F	VAL392
F	HOH9894

site_id	LD5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 9495

Chain	Residue
F	HOH2172
F	HOH9907
F	HOH9977

site_id	LD6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG F 9496

Chain	Residue
D	HOH3277
F	HIS143
F	ILE144
F	HOH9613

site_id	LD7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 9500

Chain	Residue
F	LYS230
F	ARG231
F	HOH9746

site_id	LD8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG F 9508

Chain	Residue
D	HOH9788
F	GLU318

site_id	LD9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG F 9513

Chain	Residue
D	ARG674
F	VAL342

site_id	MC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 9418

Chain	Residue
C	THR480

site_id	MC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9422

Chain	Residue
C	LYS915
C	LEU968
C	GLN969
C	HOH2856
D	ASP952

site_id	MC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9429

Chain	Residue
C	GLU764
C	SER765

site_id	MC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 9430

Chain	Residue
C	PRO79
C	GLN80
C	ASP81
C	MG9497

site_id	MC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9438

Chain	Residue
A	ARG41
C	GLU856
C	MET858
C	HIS860
C	GLY977

site_id	MC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9441

Chain	Residue
C	GLN567
C	LYS846

site_id	MC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9444

Chain	Residue
C	HOH2395
C	HOH2624

site_id	MC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9451

Chain	Residue
C	ARG142
C	SER161

site_id	MC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9454

Chain	Residue
C	GLU913
C	HOH2218
C	MG9364

site_id	MD1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG F 9516

Chain	Residue
F	ARG284

site_id	MD2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 9531

Chain	Residue
F	HOH9895
N	HOH2016
N	HOH9731

site_id	MD3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG F 9537

Chain	Residue
F	HOH9971

site_id	MD4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG F 9540

Chain	Residue
F	HOH2155
F	HOH9911

site_id	MD5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG F 9558

Chain	Residue
F	LYS407
F	HOH2016
F	HOH9843

site_id	MD6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG M 9206

Chain	Residue
M	GLU685
N	ASP739
N	G4P9101
N	HOH9213
N	HOH9214

site_id	MD7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN N 9104

Chain	Residue
N	CYS58
N	CYS60
N	CYS73
N	CYS76

site_id	MD8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN N 9105

Chain	Residue
N	CYS1112
N	CYS1194
N	CYS1201
N	CYS1204
N	HOH9487

site_id	MD9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG N 9205

Chain	Residue
N	ASP739
N	ASP741
N	ASP743
N	HOH9555

site_id	NC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9459

Chain	Residue
C	SER1117
C	LYS1118
D	HOH2175

site_id	NC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 9465

Chain	Residue
C	GLU1113

site_id	NC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9466

Chain	Residue
C	ASP653
C	HOH2211
C	HOH9669

site_id	NC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9474

Chain	Residue
C	GLU622
C	PRO624
C	MG9476

site_id	NC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 9476

Chain	Residue
C	MG9474

site_id	NC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 9489

Chain	Residue
C	PRO244

site_id	NC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 9493

Chain	Residue
C	HOH9616

site_id	NC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9497

Chain	Residue
C	ASP81
C	MG9430

site_id	NC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 9501

Chain	Residue
C	ASP554
C	ASN556
D	ARG1042
D	HOH9673

site_id	ND1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG N 9207

Chain	Residue
N	ARG783
N	HOH2335
N	G4P9101
N	HOH9215
N	HOH9216

site_id	ND2
Number of Residues	22
Details	BINDING SITE FOR RESIDUE G4P N 9100

Chain	Residue
C	GLU685
C	ARG879
C	MG9202
C	MG9217
D	ASN737
D	ARG783
D	LYS908
D	ARG1029
D	GLU1231
D	THR1234
D	GLN1235
D	MG9204
D	MG9214
D	MG9216
D	HOH9563
N	HOH2390
N	HOH9210
N	HOH9211
N	HOH9212
N	HOH9217
N	HOH9218
N	HOH9936

site_id	ND3
Number of Residues	22
Details	BINDING SITE FOR RESIDUE G4P N 9101

Chain	Residue
M	GLU685
M	SER878
M	ARG879
M	HOH2373
M	MG9206
M	HOH9607
N	GLU734
N	ASN737
N	ARG783
N	LYS908
N	GLY1027
N	ARG1029
N	GLU1231
N	THR1234
N	GLN1235
N	HOH2148
N	MG9207
N	HOH9213
N	HOH9215
N	HOH9216
N	HOH9234
N	HOH9248

site_id	OC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 9507

Chain	Residue
C	GLU177
C	ASN179
C	HOH9825
N	HOH9975

site_id	OC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 9509

Chain	Residue
C	ASP323
C	ASP324
C	ASN330
C	MG9367
C	HOH9923

site_id	OC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9511

Chain	Residue
C	LYS103
C	ASP104
C	HOH9779

site_id	OC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9514

Chain	Residue
C	VAL23
C	HOH2118

site_id	OC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9519

Chain	Residue
C	MG9259
C	MG9411

site_id	OC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9522

Chain	Residue
C	ARG5
C	GLU585

site_id	OC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9524

Chain	Residue
C	HOH2325
C	HOH2457
C	HOH2814

site_id	OC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 9525

Chain	Residue
C	LYS750
C	GLU796
C	GLY797
C	HOH9969

site_id	OC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9534

Chain	Residue
C	ARG8
C	MG9345
C	HOH9904

site_id	PC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 9542

Chain	Residue
C	ARG243

site_id	PC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 9549

Chain	Residue
C	HOH9768

site_id	PC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG C 9550

Chain	Residue
C	LYS1024
C	HOH2071

site_id	PC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG C 9553

Chain	Residue
C	ALA423
C	VAL427
C	HOH2372

site_id	PC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 9554

Chain	Residue
C	ILE108

site_id	PC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 9561

Chain	Residue
C	HOH2203

site_id	PC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 9102

Chain	Residue
D	CYS58
D	CYS60
D	CYS73
D	CYS76

site_id	PC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 9103

Chain	Residue
D	CYS1112
D	CYS1194
D	CYS1201
D	CYS1204

site_id	PC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9201

Chain	Residue
D	ASP739
D	ASP741
D	ASP743
D	MG9355

site_id	QC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9203

Chain	Residue
C	ASP686
D	ASP739
D	ASP741

site_id	QC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9204

Chain	Residue
D	ARG783
N	G4P9100
N	HOH9212

site_id	QC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9208

Chain	Residue
D	LEU1348
D	VAL1371
D	VAL1372
D	MET1375

site_id	QC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9211

Chain	Residue
D	GLU734
D	SER782
D	HOH2403

site_id	QC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9214

Chain	Residue
D	LYS908
D	HOH2986
N	HOH2390
N	G4P9100

site_id	QC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9215

Chain	Residue
D	LEU1160
D	ARG1164
D	ASP1170
D	HOH2063

site_id	QC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9216

Chain	Residue
N	G4P9100

site_id	QC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 9218

Chain	Residue
D	LEU465
D	PRO509
D	GLU510
D	TRP511
D	MET512
D	ILE513

site_id	QC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 9220

Chain	Residue
D	SER429
D	ASP430
D	VAL431
D	TYR432
D	HOH2014
D	MG9294

site_id	RC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9225

Chain	Residue
D	THR1196
D	ARG1197
D	TYR1198
D	GLY1199

site_id	RC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 9226

Chain	Residue
D	GLY418
D	ASP419
D	HOH2315
K	HOH1813
K	HOH2111
K	HOH2890

site_id	RC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9232

Chain	Residue
D	ILE827
D	ASP862
D	VAL863

site_id	RC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 9233

Chain	Residue
D	ILE956
D	LYS960
D	SER1060
D	GLU1063
D	MG9455
D	HOH9638

site_id	RC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9234

Chain	Residue
D	LYS1047
D	PRO1048
D	LYS1079
D	HOH9744

site_id	RC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9236

Chain	Residue
C	GLU685
D	CYS733
D	ALA738
N	HOH9208

site_id	RC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9237

Chain	Residue
D	LEU639
D	SER765
D	ALA766

site_id	RC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9240

Chain	Residue
D	ASN1010
D	GLU1013
D	ASN1014
D	HOH2411

site_id	RC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 9241

Chain	Residue
D	LEU250
D	HOH2004
D	HOH2447
D	HOH2469
D	MG9265

site_id	SC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 9242

Chain	Residue
D	GLY1218
D	ALA1474
D	GLY1475
D	THR1476
E	TYR17

site_id	SC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9246

Chain	Residue
D	HOH2064
D	HOH2924

site_id	SC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 9247

Chain	Residue
D	TYR215
D	VAL216
D	LYS217
D	HIS388
D	GLU389

site_id	SC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9248

Chain	Residue
D	PHE251

site_id	SC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9252

Chain	Residue
D	ALA379
D	HOH2328

site_id	SC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9253

Chain	Residue
D	ALA735
D	PHE736
D	ASN737
D	HOH2221

site_id	SC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9258

Chain	Residue
D	ARG1213
D	HOH2272
D	MG9498
D	HOH9594

site_id	SC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9261

Chain	Residue
D	ILE32
D	MET527
D	MG9546

site_id	SC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9262

Chain	Residue
D	HIS696
D	GLY697
E	ASN59

site_id	TC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9265

Chain	Residue
D	LEU250
D	MG9241

site_id	TC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9269

Chain	Residue
D	GLN1441
D	ASN1442
D	HOH3067

site_id	TC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9271

Chain	Residue
D	LEU964
D	ARG1058
D	HOH3009

site_id	TC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9274

Chain	Residue
D	MET869
D	GLU893
D	HOH2336

site_id	TC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9276

Chain	Residue
D	ARG150
D	LEU468
D	HOH3301

site_id	TC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9277

Chain	Residue
C	GLU551
D	GLY1064
D	LEU1065
D	THR1066

site_id	TC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9279

Chain	Residue
D	PRO208
D	ARG209
D	HOH2352
D	HOH2429

site_id	TC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9283

Chain	Residue
D	ARG87
D	TYR88
D	LEU524

site_id	TC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9285

Chain	Residue
D	TYR163
D	GLU436

site_id	UC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9286

Chain	Residue
D	VAL829
D	ALA830
D	HOH9944

site_id	UC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9291

Chain	Residue
D	THR1004
D	ARG1036

site_id	UC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 9294

Chain	Residue
D	ARG399
D	SER429
D	ASP430
D	TYR432
D	MG9220
D	HOH9698

site_id	UC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 9296

Chain	Residue
C	LEU952
C	LYS971
D	ASP953
D	PRO1019
D	HOH9611

site_id	UC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9301

Chain	Residue
D	THR1382
D	ALA1416
D	TRP1417
D	LYS1418

site_id	UC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9304

Chain	Residue
D	TRP1417

site_id	UC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9307

Chain	Residue
D	PRO39
D	ASP46
D	GLU47

site_id	UC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9308

Chain	Residue
D	GLN1235
D	MG9317
D	MG9393

site_id	UC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 9312

Chain	Residue
D	ASN1116
D	ARG1189
D	SER1190
D	THR1193
D	CYS1204

site_id	VC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9314

Chain	Residue
D	LEU223
D	ARG224
D	GLY364
D	ASP365

site_id	VC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9315

Chain	Residue
A	GLN16
D	GLN1184

site_id	VC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9317

Chain	Residue
D	MG9308
D	MG9393

site_id	VC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 9319

Chain	Residue
D	ASN33
D	TYR34
D	ARG35
D	HOH2434
M	GLU527

site_id	VC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9322

Chain	Residue
D	GLN1359

site_id	VC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9325

Chain	Residue
D	MG9535

site_id	VC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9331

Chain	Residue
D	GLU1351
D	LYS1354
D	HOH2126
D	HOH2827

site_id	VC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9332

Chain	Residue
D	ALA1438

site_id	VC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9333

Chain	Residue
D	HOH3129
D	HOH9894

site_id	WC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9336

Chain	Residue
D	GLU1013
D	HOH2246
D	HOH2611
D	MG9372

site_id	WC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9337

Chain	Residue
D	GLY70
D	GLU79
D	HOH2046

site_id	WC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 9342

Chain	Residue
D	GLU891
D	HOH2077
D	HOH2492
D	HOH2576
D	MG9478

site_id	WC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9343

Chain	Residue
D	GLU382
D	GLY383

site_id	WC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9349

Chain	Residue
D	VAL1400
D	GLU1401
D	HOH2089

site_id	WC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9350

Chain	Residue
D	ILE378
D	HOH2848

site_id	WC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9351

Chain	Residue
P	HIS170

site_id	WC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9353

Chain	Residue
D	LYS800
D	ALA802
D	LEU804
D	VAL829

site_id	WC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9355

Chain	Residue
D	MG9201

site_id	XC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9357

Chain	Residue
D	HOH2412
D	HOH2515
D	HOH2662

site_id	XC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9360

Chain	Residue
D	ALA814
D	HOH3250

site_id	XC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9361

Chain	Residue
D	GLU476
D	HOH2599
D	HOH2942

site_id	XC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9362

Chain	Residue
D	LYS799
D	HOH2312
D	HOH2323

site_id	XC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9363

Chain	Residue
D	HOH2786
D	HOH3237
L	LYS102
L	HOH6572

site_id	XC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9369

Chain	Residue
D	HOH2445

site_id	XC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9370

Chain	Residue
D	ASP892
D	GLU893
D	LYS894
D	HOH2527

site_id	XC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9372

Chain	Residue
D	MG9336

site_id	XC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9376

Chain	Residue
D	ASP542
D	THR592
D	HOH2979
D	HOH9883

site_id	YC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9377

Chain	Residue
D	ASP1111
D	CYS1112
D	ARG1189

site_id	YC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 9379

Chain	Residue
D	VAL1055
D	HOH2634
D	HOH3062
D	MG9470

site_id	YC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 9380

Chain	Residue
D	SER1059
D	GLU1063
D	HOH2237
D	HOH3141
D	MG9455

site_id	YC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9384

Chain	Residue
D	HOH2269
D	HOH2514
D	MG9499

site_id	YC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9386

Chain	Residue
D	ASP117
D	LEU118

site_id	YC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9390

Chain	Residue
D	GLY1298
D	HOH2614
D	MG9439

site_id	YC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9391

Chain	Residue
P	LYS226

site_id	YC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 9392

Chain	Residue
D	GLU1497
D	LYS1500
D	GLU1501
D	HOH3058
D	MG9515

site_id	YC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9393

Chain	Residue
D	MG9308
D	MG9317
N	HOH2575

site_id	ZC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9399

Chain	Residue
D	LYS149
D	ARG150
D	HOH2013

site_id	ZC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9401

Chain	Residue
N	LYS1304

site_id	ZC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9402

Chain	Residue
D	ALA822
D	HOH2804

site_id	ZC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9403

Chain	Residue
D	PHE1299
D	SER1300

site_id	ZC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9404

Chain	Residue
D	ARG534

site_id	ZC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 9406

Chain	Residue
D	ASP406

site_id	ZC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG D 9409

Chain	Residue
D	TYR1015
D	HOH3281

site_id	ZC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 9410

Chain	Residue
D	ARG1130
D	HOH2581
D	HOH9828

site_id	ZC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 9416

Chain	Residue
D	TYR401
D	VAL415
D	ALA416
D	ASN442
D	HOH2959

Functional Information from PROSITE/UniProt

site_id	PS00716
Number of Residues	27
Details	SIGMA70_2 Sigma-70 factors family signature 2. TleEVGaffgVTrerIrQIEnkaLrkL

Chain	Residue	Details
F	THR382-LEU408

site_id	PS00867
Number of Residues	8
Details	CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. LIEANLRL

Chain	Residue	Details
F	LEU187-LEU194

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKLANrHGNKGV

Chain	Residue	Details
C	GLY836-VAL848

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	912
Details	Region: {"description":"Alpha N-terminal domain (alpha-NTD)"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	22
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01322","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	70
Details	Region: {"description":"Sigma-70 factor domain-1"}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	140
Details	Region: {"description":"Sigma-70 factor domain-2"}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	156
Details	Region: {"description":"Sigma-70 factor domain-3"}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	6
Details	Motif: {"description":"Interaction with polymerase core subunit RpoC"}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)