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1S9D

ARF1[DELTA 1-17]-GDP-MG IN COMPLEX WITH BREFELDIN A AND A SEC7 DOMAIN

Replaces:  1R8R
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ADP-Ribosylation Factor 1polymer16418822.51UniProt (P84080)
Pfam (PF00025)
Bos taurus (cattle)
2B
(E)
Arnopolymer20323514.81UniProt (Q99418)
Pfam (PF01369)
Homo sapiens (human)ARF nucleotide-binding site opener, Cytohesin 2, ARF exchange factor
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
5E
(A)
1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONEnon-polymer280.41Chemie (AFB)
6F, G
(A, E)
waterwater18.0286Chemie (HOH)
Sequence modifications
E: 50 - 252 (UniProt: Q99418)
PDBExternal DatabaseDetails
Cme 174Cys 174modified residue
Tyr 190Phe 190engineered mutation
Ser 191Ala 191engineered mutation
Asp 198Ser 198engineered mutation
Met 208Pro 208engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight42337.2
Non-Polymers*Number of molecules3
Total formula weight747.9
All*Total formula weight43085.1
*Water molecules are not included.

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PDB entries from 2024-12-18

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