1RE0
Structure of ARF1-GDP bound to Sec7 domain complexed with Brefeldin A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ADP-ribosylation factor 1 | polymer | 164 | 18822.5 | 1 | UniProt (P32889) Pfam (PF00025) UniProt (by SIFTS) (P84077) | Homo sapiens (human) | |
| 2 | B (B) | ARF guanine-nucleotide exchange factor 1 | polymer | 221 | 25418.9 | 1 | UniProt (P47102) Pfam (PF01369) | Saccharomyces cerevisiae (baker's yeast) | |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 5 | E (A) | 1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE | non-polymer | 280.4 | 1 | Chemie (AFB) | |||
| 6 | F (A) | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
| 7 | G, H (A, B) | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
B: 101 - 315 (UniProt: P47102)
| PDB | External Database | Details |
|---|---|---|
| Gly 95 | - | cloning artifact |
| Ser 96 | - | cloning artifact |
| His 97 | - | cloning artifact |
| Met 98 | - | cloning artifact |
| Ala 99 | - | cloning artifact |
| Ser 100 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44241.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 940.0 | |
| All* | Total formula weight | 45181.4 |
