1RCJ
Crystal structure of E166A mutant of SHV-1 beta-lactamase with the trans-enamine intermediate of tazobactam
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Beta-lactamase SHV-1 | polymer | 265 | 28849.0 | 1 | UniProt (P14557) Pfam (PF00144) Pfam (PF13354) UniProt (by SIFTS) (P0AD64) In PDB | Klebsiella pneumoniae | PIT-2 |
| 2 | A | CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE | non-polymer | 508.6 | 2 | Chemie (MA4) | |||
| 3 | A | TAZOBACTAM TRANS-ENAMINE INTERMEDIATE | non-polymer | 302.3 | 1 | Chemie (TBI) | |||
| 4 | water | water | 18.0 | 300 | Chemie (HOH) |
Sequence modifications
A: 26 - 292 (UniProt: P14557)
| PDB | External Database | Details |
|---|---|---|
| Ala 166 | Glu 162 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28849.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1319.5 | |
| All* | Total formula weight | 30168.5 |
