Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008800 | molecular_function | beta-lactamase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017001 | biological_process | antibiotic catabolic process |
| A | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
| A | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE MA4 A 400 |
| Chain | Residue |
| A | ARG93 |
| A | ALA284 |
| A | GLU288 |
| A | HOH503 |
| A | HOH538 |
| A | HOH555 |
| A | HOH588 |
| A | HOH610 |
| A | HOH625 |
| A | HOH643 |
| A | HIS96 |
| A | ARG98 |
| A | VAL224 |
| A | PRO226 |
| A | ALA248 |
| A | VAL261 |
| A | ILE263 |
| A | ALA280 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MA4 A 401 |
| Chain | Residue |
| A | ARG244 |
| A | ILE279 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TBI A 501 |
| Chain | Residue |
| A | MET69 |
| A | SER70 |
| A | TYR105 |
| A | ASN132 |
| A | ASN170 |
| A | GLY236 |
| A | ALA237 |
| A | HOH550 |
| A | HOH766 |
Functional Information from PROSITE/UniProt
| site_id | PS00146 |
| Number of Residues | 16 |
| Details | BETA_LACTAMASE_A Beta-lactamase class-A active site. FpMMSTfKvvlCGAVL |
| Chain | Residue | Details |
| A | PHE66-LEU81 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile; acyl-ester intermediate","evidences":[{"source":"UniProtKB","id":"A0A5R8T042","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU10101","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"A0A5R8T042","evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1btl |
| Chain | Residue | Details |
| A | ALA166 | |
| A | LYS73 | |
| A | SER130 | |
| A | SER70 | |
