1R8Q
FULL-LENGTH ARF1-GDP-MG IN COMPLEX WITH BREFELDIN A AND A SEC7 DOMAIN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | ADP-ribosylation factor 1 | polymer | 181 | 20721.7 | 2 | UniProt (P84080) Pfam (PF00025) In PDB | Bos taurus (cattle) | |
| 2 | E, F | Arno | polymer | 203 | 23438.6 | 2 | UniProt (Q99418) Pfam (PF01369) In PDB | Homo sapiens (human) | ARF nucleotide-binding site opener, cytohesin 2, ARF exchange factor |
| 3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | A, B | GUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (G3D) | |||
| 5 | A, B | 1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE | non-polymer | 280.4 | 2 | Chemie (AFB) | |||
| 6 | E | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 7 | water | water | 18.0 | 345 | Chemie (HOH) |
Sequence modifications
E, F: 50 - 252 (UniProt: Q99418)
| PDB | External Database | Details |
|---|---|---|
| Tyr 190 | Phe 190 | engineered mutation |
| Ser 191 | Ala 191 | engineered mutation |
| Asp 198 | Ser 198 | engineered mutation |
| Met 208 | Pro 208 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 88320.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1721.1 | |
| All* | Total formula weight | 90041.9 |
