1R8Q
FULL-LENGTH ARF1-GDP-MG IN COMPLEX WITH BREFELDIN A AND A SEC7 DOMAIN
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000139 | cellular_component | Golgi membrane |
A | 0002090 | biological_process | regulation of receptor internalization |
A | 0003924 | molecular_function | GTPase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005525 | molecular_function | GTP binding |
A | 0005794 | cellular_component | Golgi apparatus |
A | 0005829 | cellular_component | cytosol |
A | 0005886 | cellular_component | plasma membrane |
A | 0006886 | biological_process | intracellular protein transport |
A | 0014069 | cellular_component | postsynaptic density |
A | 0015031 | biological_process | protein transport |
A | 0016020 | cellular_component | membrane |
A | 0016192 | biological_process | vesicle-mediated transport |
A | 0016787 | molecular_function | hydrolase activity |
A | 0034315 | biological_process | regulation of Arp2/3 complex-mediated actin nucleation |
A | 0042583 | cellular_component | chromaffin granule |
A | 0043005 | cellular_component | neuron projection |
A | 0045202 | cellular_component | synapse |
A | 0060292 | biological_process | long-term synaptic depression |
A | 0097061 | biological_process | dendritic spine organization |
B | 0000139 | cellular_component | Golgi membrane |
B | 0002090 | biological_process | regulation of receptor internalization |
B | 0003924 | molecular_function | GTPase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005525 | molecular_function | GTP binding |
B | 0005794 | cellular_component | Golgi apparatus |
B | 0005829 | cellular_component | cytosol |
B | 0005886 | cellular_component | plasma membrane |
B | 0006886 | biological_process | intracellular protein transport |
B | 0014069 | cellular_component | postsynaptic density |
B | 0015031 | biological_process | protein transport |
B | 0016020 | cellular_component | membrane |
B | 0016192 | biological_process | vesicle-mediated transport |
B | 0016787 | molecular_function | hydrolase activity |
B | 0034315 | biological_process | regulation of Arp2/3 complex-mediated actin nucleation |
B | 0042583 | cellular_component | chromaffin granule |
B | 0043005 | cellular_component | neuron projection |
B | 0045202 | cellular_component | synapse |
B | 0060292 | biological_process | long-term synaptic depression |
B | 0097061 | biological_process | dendritic spine organization |
E | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
E | 0032012 | biological_process | regulation of ARF protein signal transduction |
F | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
F | 0032012 | biological_process | regulation of ARF protein signal transduction |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG A 402 |
Chain | Residue |
A | THR31 |
A | G3D401 |
A | HOH410 |
A | HOH450 |
A | HOH504 |
A | HOH510 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG B 502 |
Chain | Residue |
B | HOH563 |
B | HOH567 |
B | HOH570 |
B | THR31 |
B | G3D501 |
B | HOH517 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN E 601 |
Chain | Residue |
E | HIS127 |
E | ASP131 |
F | HIS127 |
F | ASP131 |
site_id | AC4 |
Number of Residues | 21 |
Details | BINDING SITE FOR RESIDUE G3D A 401 |
Chain | Residue |
A | ALA27 |
A | ALA28 |
A | GLY29 |
A | LYS30 |
A | THR31 |
A | THR32 |
A | ASN126 |
A | LYS127 |
A | ASP129 |
A | LEU130 |
A | CYS159 |
A | ALA160 |
A | THR161 |
A | MG402 |
A | HOH410 |
A | HOH432 |
A | HOH435 |
A | HOH445 |
A | HOH504 |
A | HOH510 |
B | LYS142 |
site_id | AC5 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE AFB A 403 |
Chain | Residue |
A | VAL53 |
A | THR64 |
A | VAL65 |
A | TRP66 |
A | ASP67 |
A | TRP78 |
A | TYR81 |
A | HOH406 |
A | HOH414 |
E | TYR190 |
E | MET194 |
site_id | AC6 |
Number of Residues | 19 |
Details | BINDING SITE FOR RESIDUE G3D B 501 |
Chain | Residue |
A | LYS142 |
B | ALA27 |
B | ALA28 |
B | GLY29 |
B | LYS30 |
B | THR31 |
B | THR32 |
B | ASN126 |
B | LYS127 |
B | ASP129 |
B | LEU130 |
B | CYS159 |
B | ALA160 |
B | THR161 |
B | MG502 |
B | HOH563 |
B | HOH567 |
B | HOH569 |
B | HOH570 |
site_id | AC7 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE AFB B 503 |
Chain | Residue |
B | VAL53 |
B | THR64 |
B | VAL65 |
B | TRP66 |
B | ASP67 |
B | TRP78 |
B | TYR81 |
B | HOH506 |
B | HOH508 |
B | HOH513 |
F | TYR190 |
F | MET194 |
F | THR197 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000269|PubMed:14654833, ECO:0000269|PubMed:24058294, ECO:0007744|PDB:1R8Q, ECO:0007744|PDB:1R8S, ECO:0007744|PDB:1S9D, ECO:0007744|PDB:4C0A |
Chain | Residue | Details |
A | GLY24 | |
A | ASN126 | |
A | ALA160 | |
B | GLY24 | |
B | ASN126 | |
B | ALA160 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | MOD_RES: N-acetylglycine; alternate => ECO:0000250|UniProtKB:P84077 |
Chain | Residue | Details |
A | GLY2 | |
B | GLY2 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | LIPID: N-myristoyl glycine; alternate => ECO:0000250|UniProtKB:P84077 |
Chain | Residue | Details |
A | GLY2 | |
B | GLY2 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1ksj |
Chain | Residue | Details |
A | GLN71 |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1ksj |
Chain | Residue | Details |
B | GLN71 |