1Q3X
Crystal structure of the catalytic region of human MASP-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Mannan-binding lectin serine protease 2 | polymer | 328 | 35756.3 | 2 | UniProt (O00187) Pfam (PF00084) Pfam (PF00089) | Homo sapiens (human) | Mannose-binding protein associated serine protease 2, MASP-2, MBL-associated serine protease 2 |
| 2 | C, H (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 3 | D, E, F, G, I... (A, B) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) PubChem (753) | |||
| 4 | L, M (A, B) | water | water | 18.0 | 362 | Chemie (HOH) |
Sequence modifications
A, B: 359 - 686 (UniProt: O00187)
| PDB | External Database | Details |
|---|---|---|
| Ala 359 | - | cloning artifact |
| Ser 360 | - | cloning artifact |
| Met 361 | - | cloning artifact |
| Thr 362 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71512.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 690.6 | |
| All* | Total formula weight | 72203.3 |
