Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 800 |
| Chain | Residue |
| A | SER657 |
| A | ASN659 |
| A | HOH804 |
| A | HOH805 |
| A | HOH806 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 850 |
| Chain | Residue |
| B | HOH855 |
| B | HOH1018 |
| B | ASP627 |
| B | SER657 |
| B | ASN659 |
| B | HOH854 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 700 |
| Chain | Residue |
| A | PRO432 |
| A | TYR474 |
| A | PRO550 |
| A | ILE551 |
| A | CYS552 |
| A | LEU553 |
| A | HOH900 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 701 |
| Chain | Residue |
| A | SER628 |
| A | CYS629 |
| A | ARG630 |
| A | SER633 |
| A | VAL653 |
| A | SER654 |
| A | TRP655 |
| A | HOH803 |
| A | HOH829 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 702 |
| Chain | Residue |
| A | PRO507 |
| A | HIS508 |
| A | TYR509 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 703 |
| Chain | Residue |
| A | LEU553 |
| A | ARG555 |
| A | ASP641 |
| A | THR644 |
| A | ARG646 |
| A | PHE648 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 750 |
| Chain | Residue |
| B | PRO432 |
| B | TYR474 |
| B | PRO550 |
| B | ILE551 |
| B | CYS552 |
| B | LEU553 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 751 |
| Chain | Residue |
| B | SER628 |
| B | CYS629 |
| B | ARG630 |
| B | SER633 |
| B | VAL653 |
| B | TRP655 |
| B | HOH851 |
| B | HOH853 |
| B | HOH883 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 754 |
| Chain | Residue |
| B | TYR474 |
| B | ASN476 |
| B | TRP477 |
| B | ILE683 |
| B | PHE686 |
Functional Information from PROSITE/UniProt
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScrGDSGGALV |
| Chain | Residue | Details |
| A | ASP627-VAL638 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 68 |
| Details | Domain: {"description":"Sushi 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 478 |
| Details | Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"15364579","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"15364579","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23386610","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP532 | |
| A | SER633 | |
| A | HIS483 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | ASP532 | |
| B | SER633 | |
| B | HIS483 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP532 | |
| A | SER633 | |
| A | HIS483 | |
| A | GLY631 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | ASP532 | |
| B | SER633 | |
| B | HIS483 | |
| B | GLY631 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | GLY634 | |
| A | ASP532 | |
| A | SER633 | |
| A | HIS483 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | GLY634 | |
| B | ASP532 | |
| B | SER633 | |
| B | HIS483 | |
| site_id | CSA7 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP532 | |
| A | SER633 | |
| A | HIS483 | |
| A | SER654 | |
| A | GLY631 | |
| site_id | CSA8 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| B | ASP532 | |
| B | SER633 | |
| B | HIS483 | |
| B | SER654 | |
| B | GLY631 | |
1Q3X
