1Q1G
Crystal structure of Plasmodium falciparum PNP with 5'-methylthio-immucillin-H
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Uridine phosphorylase putative | polymer | 276 | 30502.0 | 6 | UniProt (Q8I3X4) Pfam (PF01048) In PDB | Plasmodium falciparum | |
| 2 | D, E, A, F, B... | SULFATE ION | non-polymer | 96.1 | 22 | Chemie (SO4) | |||
| 3 | D, E, A, F, B... | 3,4-DIHYDROXY-2-[(METHYLSULFANYL)METHYL]-5-(4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)PYRROLIDINIUM | non-polymer | 297.4 | 6 | Chemie (MTI) | |||
| 4 | D, E, A, F, B | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 9 | Chemie (IPA) | |||
| 5 | water | water | 18.0 | 357 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: -1 - 245 (UniProt: Q8I3X4)
| PDB | External Database | Details |
|---|---|---|
| Ala 0 | - | cloning artifact |
| Leu 1 | - | cloning artifact |
| Lys 246 | - | cloning artifact |
| Gly 247 | - | cloning artifact |
| Glu 248 | - | cloning artifact |
| Phe 249 | - | cloning artifact |
| Glu 250 | - | cloning artifact |
| Ala 251 | - | cloning artifact |
| Tyr 252 | - | cloning artifact |
| Val 253 | - | cloning artifact |
| Glu 254 | - | cloning artifact |
| Gln 255 | - | cloning artifact |
| Lys 256 | - | cloning artifact |
| Leu 257 | - | cloning artifact |
| Ile 258 | - | cloning artifact |
| Ser 259 | - | cloning artifact |
| Glu 260 | - | cloning artifact |
| Glu 261 | - | cloning artifact |
| Asp 262 | - | cloning artifact |
| Leu 263 | - | cloning artifact |
| Asn 264 | - | cloning artifact |
| Ser 265 | - | cloning artifact |
| Ala 266 | - | cloning artifact |
| Val 267 | - | cloning artifact |
| Asp 268 | - | cloning artifact |
| His 269 | - | expression tag |
| His 270 | - | expression tag |
| His 271 | - | expression tag |
| His 272 | - | expression tag |
| His 273 | - | expression tag |
| His 274 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 183012.2 | |
| Non-Polymers* | Number of molecules | 37 |
| Total formula weight | 4438.4 | |
| All* | Total formula weight | 187450.6 |
