1Q0L
Crystal structure of DXR in complex with fosmidomycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | polymer | 406 | 44404.9 | 1 | UniProt (P45568) Pfam (PF02670) Pfam (PF08436) Pfam (PF13288) | Escherichia coli | DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, IspC |
| 2 | B (A) | 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID | non-polymer | 183.1 | 1 | Chemie (FOM) | |||
| 3 | C (A) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 4 | D (A) | water | water | 18.0 | 91 | Chemie (HOH) |
Sequence modifications
A: 1 - 398 (UniProt: P45568)
| PDB | External Database | Details |
|---|---|---|
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44404.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 928.5 | |
| All* | Total formula weight | 45333.4 |
