1Q0L

Crystal structure of DXR in complex with fosmidomycin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	1-deoxy-D-xylulose 5-phosphate reductoisomerase	polymer	406	44404.9	1	UniProt (P45568) Pfam (PF02670) Pfam (PF08436) Pfam (PF13288) In PDB	Escherichia coli	DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, IspC
2	A	3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID	non-polymer		183.1	1	Chemie (FOM)
3	A	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	1	Chemie (NDP)
4		water	water		18.0	91	Chemie (HOH)

Sequence modifications

A: 1 - 398 (UniProt: P45568)

PDB	External Database	Details
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44404.9
Non-Polymers*	Number of molecules	2
	Total formula weight	928.5
All*	Total formula weight	45333.4

*Water molecules are not included.