1PZM

Crystal structure of HGPRT-ase from Leishmania tarentolae in complex with GMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	hypoxanthine-guanine phosphoribosyltransferase	polymer	211	23660.5	2	UniProt (Q9NJI5)	Leishmania tarentolae	HGPRT
2	C, D (A, B)	GUANOSINE-5'-MONOPHOSPHATE	non-polymer		363.2	2	Chemie (5GP)
3	E, F (A, B)	water	water		18.0	243	Chemie (HOH)

Sequence modifications

A, B: 1 - 211 (UniProt: Q9NJI5)

PDB	External Database	Details
Arg 176	His 176	conflict
Gly 183	Val 183	conflict
Met 184	Trp 184	conflict
Asp 185	Thr 185	conflict
Glu 188	Asp 188	conflict
Ser 189	-	insertion
Tyr 190	Leu 189	conflict
Glu 192	Gly 191	conflict
Leu 193	Val 192	conflict
Arg 194	Pro 193	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47320.9
Non-Polymers*	Number of molecules	2
	Total formula weight	726.4
All*	Total formula weight	48047.4

*Water molecules are not included.