1PY2
Structure of a 60 nM Small Molecule Bound to a Hot Spot on IL-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Interleukin-2 | polymer | 132 | 15334.9 | 4 | UniProt (P60568) Pfam (PF00715) | Homo sapiens (human) | IL-2, T-cell growth factor, TCGF, Aldesleukin |
| 2 | E, H, J, K (A, B, C, D) | 5-[2,3-DICHLORO-4-(5-{1-[2-(2-GUANIDINO-4-METHYL-PENTANOYLAMINO)-ACETYL]-PIPERIDIN-4-YL}-1-METHYL-1H-PYRAZOL-3-YL)-PHENOXYMETHYL]-FURAN-2-CARBOXYLIC ACID | non-polymer | 662.6 | 4 | Chemie (FRH) | |||
| 3 | F, G, I (B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 61339.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 2846.5 | |
| All* | Total formula weight | 64186.0 |
