1PX5
Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 2'-5'-oligoadenylate synthetase 1 | polymer | 349 | 40419.4 | 2 | UniProt (Q29599) Pfam (PF01909) Pfam (PF10421) | Sus scrofa (pig) | (2-5')oligo(A)synthetase 1, 2-5A synthetase 1, p42 OAS |
| 2 | C, D, E, F (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | G, H (A, B) | water | water | 18.0 | 770 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 349 (UniProt: Q29599)
| PDB | External Database | Details |
|---|---|---|
| Ycm 24 | Cys 24 | modified residue |
| Ycm 37 | Cys 37 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 80838.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 384.3 | |
| All* | Total formula weight | 81223.1 |






