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1PX5

Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
2'-5'-oligoadenylate synthetase 1polymer34940419.42UniProt (Q29599)
Pfam (PF01909)
Pfam (PF10421)
Sus scrofa (pig)(2-5')oligo(A)synthetase 1, 2-5A synthetase 1, p42 OAS
2C, D, E, F
(A, B)
SULFATE IONnon-polymer96.14Chemie (SO4)
3G, H
(A, B)
waterwater18.0770Chemie (HOH)
Sequence modifications
A, B: 1 - 349 (UniProt: Q29599)
PDBExternal DatabaseDetails
Ycm 24Cys 24modified residue
Ycm 37Cys 37modified residue
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight80838.9
Non-Polymers*Number of molecules4
Total formula weight384.3
All*Total formula weight81223.1
*Water molecules are not included.

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PDB entries from 2026-03-11

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