1P9M
Crystal structure of the hexameric human IL-6/IL-6 alpha receptor/gp130 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Interleukin-6 receptor beta chain | polymer | 299 | 34099.5 | 1 | UniProt (P40189) Pfam (PF06328) Pfam (PF09240) Pfam (PF00041) In PDB | Homo sapiens (human) | IL-6R-beta, Interleukin 6 signal transducer, Membrane glycoprotein 130, GP130, Oncostatin M receptor, CDw130, CD130 antigen |
| 2 | B | Interleukin-6 | polymer | 186 | 21103.1 | 1 | UniProt (P05231) Pfam (PF00489) In PDB | Homo sapiens (human) | IL-6, B-cell stimulatory factor 2, BSF-2, Interferon beta-2, Hybridoma growth factor |
| 3 | C | Interleukin-6 receptor alpha chain | polymer | 201 | 23050.9 | 1 | UniProt (P08887) Pfam (PF09240) In PDB | Homo sapiens (human) | IL-6R-alpha, IL-6R 1, CD126 antigen |
Sequence modifications
B: 1 - 184 (UniProt: P05231)
| PDB | External Database | Details |
|---|---|---|
| Ala -1 | - | cloning artifact |
| Pro 0 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 78253.5 | |
| All* | Total formula weight | 78253.5 |
