1NVP

HUMAN TFIIA/TBP/DNA COMPLEX

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (E)	5'-D(*GP*GP*GP*GP*GP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*G)-3'	polymer	17	5381.5	1
2	B (F)	5'-D(*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*CP*CP*CP*CP*C)-3'	polymer	17	5034.3	1
3	C (A)	TATA box binding protein	polymer	181	20443.3	1	UniProt (P20226) Pfam (PF00352)	Homo sapiens (human)	Transcription initiation factor TFIID, TATA-box factor, TATA sequence-binding protein, TBP
4	D (B)	Transcription initiation factor IIA alpha chain	polymer	57	6486.3	1	UniProt (P52655)	Homo sapiens (human)	TFIIA p35 and p19 subunits, TFIIA-42, TFIIAL
5	E (C)	Transcription initiation factor IIA beta chain	polymer	76	8687.4	1	UniProt (P52655) Pfam (PF03153)	Homo sapiens (human)	TFIIA p35 and p19 subunits, TFIIA-42, TFIIAL
6	F (D)	Transcription initiation factor IIA gamma chain	polymer	108	12337.9	1	UniProt (P52657) Pfam (PF02268) Pfam (PF02751)	Homo sapiens (human)	TFIIA P12 subunit, TFIIA-12, TFIIAS, TFIIA-gamma
7	G, H, I, J, K... (E, F, A, B, C...)	water	water		18.0	231	Chemie (HOH)

Sequence modifications

C: 303 - 376 (UniProt: P52655)

PDB	External Database	Details
Gly 301	-	cloning artifact
Ser 302	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	58370.5
All*	Total formula weight	58370.5

*Water molecules are not included.