1NVP

HUMAN TFIIA/TBP/DNA COMPLEX

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0006352	biological_process	DNA-templated transcription initiation
B	0005672	cellular_component	transcription factor TFIIA complex
B	0006367	biological_process	transcription initiation at RNA polymerase II promoter
C	0005672	cellular_component	transcription factor TFIIA complex
C	0006367	biological_process	transcription initiation at RNA polymerase II promoter
D	0001091	molecular_function	RNA polymerase II general transcription initiation factor binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005669	cellular_component	transcription factor TFIID complex
D	0005672	cellular_component	transcription factor TFIIA complex
D	0006366	biological_process	transcription by RNA polymerase II
D	0006367	biological_process	transcription initiation at RNA polymerase II promoter
D	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
D	0017025	molecular_function	TBP-class protein binding
D	0030054	cellular_component	cell junction
D	0042803	molecular_function	protein homodimerization activity
D	0045944	biological_process	positive regulation of transcription by RNA polymerase II
D	0046982	molecular_function	protein heterodimerization activity
D	0051123	biological_process	RNA polymerase II preinitiation complex assembly
D	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
D	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding

Functional Information from PROSITE/UniProt

site_id	PS00351
Number of Residues	50
Details	TFIID Transcription factor TFIID repeat signature. YnPkrFaaVImRirePRttaLIFsSGKMvctGAKseeqsrlAarkyarvV

Chain	Residue	Details
A	TYR192-VAL241
A	TYR283-LEU332

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:27193682, ECO:0007744|PDB:5IYD

Chain	Residue	Details
C	HIS343
C	ARG344
A	LYS218
A	ASN257
A	ARG294

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine; by TAF1 => ECO:0000269|PubMed:11278496, ECO:0007744|PubMed:17081983

Chain	Residue	Details
C	SER316
C	SER321

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