1NVP

HUMAN TFIIA/TBP/DNA COMPLEX

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0006352	biological_process	DNA-templated transcription initiation
B	0005672	cellular_component	transcription factor TFIIA complex
B	0006367	biological_process	transcription initiation at RNA polymerase II promoter
C	0005672	cellular_component	transcription factor TFIIA complex
C	0006367	biological_process	transcription initiation at RNA polymerase II promoter
D	0001091	molecular_function	RNA polymerase II general transcription initiation factor binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005669	cellular_component	transcription factor TFIID complex
D	0005672	cellular_component	transcription factor TFIIA complex
D	0006351	biological_process	DNA-templated transcription
D	0006366	biological_process	transcription by RNA polymerase II
D	0006367	biological_process	transcription initiation at RNA polymerase II promoter
D	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
D	0017025	molecular_function	TBP-class protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0045944	biological_process	positive regulation of transcription by RNA polymerase II
D	0046982	molecular_function	protein heterodimerization activity
D	0051123	biological_process	RNA polymerase II preinitiation complex assembly
D	0060261	biological_process	positive regulation of transcription initiation by RNA polymerase II
D	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding

Functional Information from PROSITE/UniProt

site_id	PS00351
Number of Residues	50
Details	TFIID Transcription factor TFIID repeat signature. YnPkrFaaVImRirePRttaLIFsSGKMvctGAKseeqsrlAarkyarvV

Chain	Residue	Details
A	TYR192-VAL241
A	TYR283-LEU332

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	76
Details	Repeat: {"description":"1"}

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Residue

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site_id	SWS_FT_FI2
Number of Residues	77
Details	Repeat: {"description":"2"}

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Residue

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site_id	SWS_FT_FI3
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27193682","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5IYD","evidenceCode":"ECO:0007744"}]}

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Residue

Details

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