1NP0
Human lysosomal beta-hexosaminidase isoform B in complex with intermediate analogue NAG-thiazoline
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Beta-hexosaminidase subunit beta | polymer | 58 | 6416.4 | 2 | UniProt (P07686) Pfam (PF14845) In PDB | Homo sapiens (Human) | Beta-N-acetylhexosaminidase subunit beta,Hexosaminidase subunit B,Cervical cancer proto-oncogene 7 protein,HCC-7,N-acetyl-beta-glucosaminidase subunit beta |
2 | C, E | Beta-hexosaminidase subunit beta chain B | polymer | 190 | 21653.6 | 2 | UniProt (P07686) Pfam (PF14845) Pfam (PF00728) In PDB | Homo sapiens (Human) | Beta-N-acetylhexosaminidase subunit beta,Hexosaminidase subunit B,Cervical cancer proto-oncogene 7 protein,HCC-7,N-acetyl-beta-glucosaminidase subunit beta |
3 | D, F | Beta-hexosaminidase subunit beta chain A | polymer | 241 | 27818.5 | 2 | UniProt (P07686) Pfam (PF00728) In PDB | Homo sapiens (Human) | Beta-N-acetylhexosaminidase subunit beta,Hexosaminidase subunit B,Cervical cancer proto-oncogene 7 protein,HCC-7,N-acetyl-beta-glucosaminidase subunit beta |
4 | G, H | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
5 | A, B | 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL | non-polymer | 219.3 | 2 | Chemie (NGT) | |||
6 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
7 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
8 | water | water | 18.0 | 244 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 111776.8 | |
Branched | Number of molecules | 2 |
Total formula weight | 848.8 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 810.9 | |
All* | Total formula weight | 113436.5 |