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1NJS

human GAR Tfase in complex with hydrolyzed form of 10-trifluoroacetyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Phosphoribosylglycinamide formyltransferasepolymer20922678.92UniProt (P22102)
Pfam (PF00551)
Homo sapiens (human)GAR TFASE, GART, GAR transformylase, 5'-phosphoribosylglycinamide transformylase
2C, D, F
(A, B)
PHOSPHATE IONnon-polymer95.03Chemie (PO4)
3E, G
(A, B)
N-{4-[(1R)-4-[(2R,4R,5S)-2,4-DIAMINO-6-OXOHEXAHYDROPYRIMIDIN-5-YL]-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYL)BUTYL]BENZOYL}-D-GLUTAMIC ACIDnon-polymer549.52Chemie (KEU)
4H, I
(A, B)
waterwater18.0251Chemie (HOH)
Sequence modifications
A, B: 1 - 203 (UniProt: P22102)
PDBExternal DatabaseDetails
His 204-expression tag
His 205-expression tag
His 206-expression tag
His 207-expression tag
His 208-expression tag
His 209-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight45357.9
Non-Polymers*Number of molecules5
Total formula weight1383.9
All*Total formula weight46741.8
*Water molecules are not included.

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PDB entries from 2025-07-30

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