1NJS

human GAR Tfase in complex with hydrolyzed form of 10-trifluoroacetyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Phosphoribosylglycinamide formyltransferase	polymer	209	22678.9	2	UniProt (P22102) Pfam (PF00551) In PDB	Homo sapiens (human)	GAR TFASE, GART, GAR transformylase, 5'-phosphoribosylglycinamide transformylase
2	A, B	PHOSPHATE ION	non-polymer		95.0	3	Chemie (PO4)
3	A, B	N-{4-[(1R)-4-[(2R,4R,5S)-2,4-DIAMINO-6-OXOHEXAHYDROPYRIMIDIN-5-YL]-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYL)BUTYL]BENZOYL}-D-GLUTAMIC ACID	non-polymer		549.5	2	Chemie (KEU)
4		water	water		18.0	251	Chemie (HOH)

Sequence modifications

A, B: 1 - 203 (UniProt: P22102)

PDB	External Database	Details
His 204	-	expression tag
His 205	-	expression tag
His 206	-	expression tag
His 207	-	expression tag
His 208	-	expression tag
His 209	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45357.9
Non-Polymers*	Number of molecules	5
	Total formula weight	1383.9
All*	Total formula weight	46741.8

*Water molecules are not included.