1NI4
HUMAN PYRUVATE DEHYDROGENASE
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Pyruvate dehydrogenase E1 component: Alpha subunit | polymer | 365 | 41277.2 | 2 | UniProt (P08559) Pfam (PF00676) In PDB | Homo sapiens (human) | PDHE1-A type I |
2 | B, D | Pyruvate dehydrogenase E1 component: Beta subunit | polymer | 341 | 37956.5 | 2 | UniProt (P11177) Pfam (PF02779) Pfam (PF02780) In PDB | Homo sapiens (human) | PDHE1-B |
3 | A, C | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
4 | A, C | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 2 | Chemie (TPP) | |||
5 | B, D | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
6 | water | water | 18.0 | 742 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 361 (UniProt: P08559)
B, D: 1 - 329 (UniProt: P11177)
PDB | External Database | Details |
---|---|---|
Met -3 | - | CLONING ARTIFACT |
Arg -2 | - | CLONING ARTIFACT |
Gly -1 | - | CLONING ARTIFACT |
Ser 0 | - | CLONING ARTIFACT |
Mse 38 | Met 67 | MODIFIED RESIDUE |
Mse 39 | Met 68 | MODIFIED RESIDUE |
Mse 45 | Met 74 | MODIFIED RESIDUE |
Mse 124 | Met 153 | MODIFIED RESIDUE |
Mse 126 | Met 155 | MODIFIED RESIDUE |
Mse 181 | Met 210 | MODIFIED RESIDUE |
Mse 200 | Met 229 | MODIFIED RESIDUE |
Mse 228 | Met 257 | MODIFIED RESIDUE |
Mse 253 | Met 282 | MODIFIED RESIDUE |
Mse 265 | Met 294 | MODIFIED RESIDUE |
Mse 289 | Met 318 | MODIFIED RESIDUE |
Mse 295 | Met 324 | MODIFIED RESIDUE |
PDB | External Database | Details |
---|---|---|
Met -11 | - | CLONING ARTIFACT |
Arg -10 | - | CLONING ARTIFACT |
Gly -9 | - | CLONING ARTIFACT |
Ser -8 | - | CLONING ARTIFACT |
His -7 | - | EXPRESSION TAG |
His -6 | - | EXPRESSION TAG |
His -5 | - | EXPRESSION TAG |
His -4 | - | EXPRESSION TAG |
His -3 | - | EXPRESSION TAG |
His -2 | - | EXPRESSION TAG |
Gly -1 | - | CLONING ARTIFACT |
Ser 0 | - | CLONING ARTIFACT |
Leu 1 | - | SEE REMARK 999 |
Mse 13 | Met 43 | MODIFIED RESIDUE |
Mse 60 | Met 90 | MODIFIED RESIDUE |
Mse 71 | Met 101 | MODIFIED RESIDUE |
Mse 81 | Met 111 | MODIFIED RESIDUE |
Mse 87 | Met 117 | MODIFIED RESIDUE |
Mse 103 | Met 133 | MODIFIED RESIDUE |
Mse 175 | Met 205 | MODIFIED RESIDUE |
Mse 238 | Met 268 | MODIFIED RESIDUE |
Mse 244 | Met 274 | MODIFIED RESIDUE |
Mse 246 | Met 276 | MODIFIED RESIDUE |
Mse 254 | Met 284 | MODIFIED RESIDUE |
Mse 280 | Met 310 | MODIFIED RESIDUE |
Mse 302 | Met 332 | MODIFIED RESIDUE |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 158467.4 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 977.4 | |
All* | Total formula weight | 159444.8 |