1N7S
High Resolution Structure of a Truncated Neuronal SNARE Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | vesicle-associated membrane protein 2 | polymer | 63 | 7231.1 | 1 | UniProt (P63045) Pfam (PF00957) | Rattus norvegicus (Norway rat) | Synaptobrevin 2 (vesicle-associated membrane protein, VAMP-2) |
| 2 | B (B) | Syntaxin 1A | polymer | 68 | 7850.9 | 1 | UniProt (P32851) Pfam (PF05739) | Rattus norvegicus (Norway rat) | Synaptotagmin associated 35 kDa protein, P35A, Neuron-specific antigen HPC-1 |
| 3 | C (C) | SNAP-25A | polymer | 79 | 9174.2 | 1 | UniProt (P60881) | Rattus norvegicus (Norway rat) | |
| 4 | D (D) | SNAP-25A | polymer | 66 | 7484.3 | 1 | UniProt (P60881) | Rattus norvegicus (Norway rat) | |
| 5 | E, G, H (A, C) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 6 | F, I (A, C) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
| 7 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 322 | Chemie (HOH) |
Sequence modifications
A: 27 - 88 (UniProt: P63045)
B: 191 - 256 (UniProt: P32851)
C: 7 - 83 (UniProt: P60881)
D: 141 - 204 (UniProt: P60881)
| PDB | External Database | Details |
|---|---|---|
| Gly 27 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 189 | - | cloning artifact |
| Ser 190 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 5 | - | cloning artifact |
| Ser 6 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 139 | - | cloning artifact |
| Ser 140 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 31740.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 356.6 | |
| All* | Total formula weight | 32097.1 |
