1N0W
Crystal structure of a RAD51-BRCA2 BRC repeat complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA repair protein RAD51 homolog 1 | polymer | 243 | 26855.3 | 1 | UniProt (Q06609) Pfam (PF08423) In PDB | Homo sapiens (human) | RAD51, hRAD51, HsRAD51 |
| 2 | B | Breast cancer type 2 susceptibility protein | polymer | 35 | 3966.6 | 1 | UniProt (P51587) Pfam (PF00634) In PDB | Homo sapiens (human) | BRCA2 BRC4 REPEAT SEQUENCE |
| 3 | L | peptide linker | polymer | 14 | 1234.1 | 1 | |||
| 4 | C | ARTIFICIAL GLY-SER-MSE-GLY PEPTIDE | polymer | 4 | 397.3 | 1 | |||
| 5 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 8 | water | water | 18.0 | 247 | Chemie (HOH) |
Sequence modifications
A: 97 - 339 (UniProt: Q06609)
| PDB | External Database | Details |
|---|---|---|
| Mse 125 | Met 125 | modified residue |
| Mse 158 | Met 158 | modified residue |
| Mse 210 | Met 210 | modified residue |
| Mse 211 | Met 211 | modified residue |
| Mse 243 | Met 243 | modified residue |
| Mse 251 | Met 251 | modified residue |
| Mse 278 | Met 278 | modified residue |
| Mse 326 | Met 326 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 32453.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 370.1 | |
| All* | Total formula weight | 32823.4 |
