1N0T
X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with the antagonist (S)-ATPO at 2.1 A resolution.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Glutamate receptor 2 | polymer | 263 | 29221.7 | 4 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) In PDB | Rattus norvegicus (Norway rat) | GluR-2, GluR-B, Glutamate receptor ionotropic, AMPA 2 |
| 2 | A, B, C, D | (S)-2-AMINO-3-(5-TERT-BUTYL-3-(PHOSPHONOMETHOXY)-4-ISOXAZOLYL)PROPIONIC ACID | non-polymer | 322.3 | 4 | Chemie (AT1) | |||
| 3 | B, C, D | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | D | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | water | water | 18.0 | 949 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 3 - 117 (UniProt: P19491)
A, B, C, D: 120 - 263 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | CLONING ARTIFACT |
| Ala 2 | - | CLONING ARTIFACT |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | LINKER |
| Thr 119 | - | LINKER |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 116886.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1732.3 | |
| All* | Total formula weight | 118619.0 |
