1MW9
Crystal Structure of H365R mutant of 67 kDA N-terminal fragment of E. coli DNA Topoisomerase I
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | DNA Topoisomerase I | polymer | 592 | 66930.8 | 1 | UniProt (P06612) Pfam (PF01751) Pfam (PF01131) | Escherichia coli | Omega-protein, Relaxing enzyme, Untwisting enzyme, Swivelase |
| 2 | B, C, D, E, F... (X) | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
| 3 | K (X) | water | water | 18.0 | 577 | Chemie (HOH) |
Sequence modifications
X: 1 - 592 (UniProt: P06612)
| PDB | External Database | Details |
|---|---|---|
| Arg 365 | His 365 | engineered mutation |
| Asn 549 | Ser 549 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 66930.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 864.6 | |
| All* | Total formula weight | 67795.4 |
