1MR1
Crystal Structure of a Smad4-Ski Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Mothers against decapentaplegic homolog 4 | polymer | 235 | 25642.3 | 2 | UniProt (Q13485) Pfam (PF03166) | Homo sapiens (human) | Smad4, Mothers against DPP homolog 4, Deletion target in pancreatic carcinoma 4, hSMAD4 |
| 2 | C, D (C, D) | Ski oncogene | polymer | 99 | 11519.2 | 2 | UniProt (P12755) Pfam (PF08782) | Homo sapiens (human) | Ski, C-ski |
| 3 | E, F (C, D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A, B: 319 - 552 (UniProt: Q13485)
C, D: 219 - 313 (UniProt: P12755)
| PDB | External Database | Details |
|---|---|---|
| Met 318 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Gly 215 | - | cloning artifact |
| Ser 216 | - | cloning artifact |
| His 217 | - | cloning artifact |
| Met 218 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 74323.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 74453.8 |
